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Volume 6, Number 5—October 2000


Antimicrobial-Drug Use and Changes in Resistance in Streptococcus pneumoniae

Daniel J. DiekemaComments to Author , Angela B. Brueggemann, and Gary V. Doern
Author affiliations: University of Iowa College of Medicine, Iowa City, Iowa

Main Article

Table 4

Analysis of covariance model, with change in penicillin resistance at each of the 23 medical centers as the dependent variable

Source Type III sums of squares Parameter estimate (B) F p-value
Overall model 990a 4.8 0.02
Intercept 56 4.5 0.5 0.47
ß-lactam use 893 8.6 8.7 0.008
Macrolide use 553 -6.7 5.4 0.031
Error 2,054
Total 4,616
Corrected total 3,045

aR2 = 0.325

Main Article