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Volume 7, Number 2—April 2001
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections

State of the Art

Molecular Approaches to Diagnosing and Managing Infectious Diseases: Practicality and Costs

Michael A. PfallerComments to Author 
Author affiliation: University of Iowa College of Medicine, Iowa City, Iowa, USA

Main Article

Table 2

Noncommercial nucleic acid-based tests for clinically important viral and bacterial pathogensa

Organism Specimen type Clinical indication
Epstein-Barr virus (EBV) Cerebrospinal fluid (CSF) EBV lymphoproliferative disorder
Herpes simplex virus
(HSV) types 1 and 2 CSF
Vitreous humor Encephalitis
Varicella-zoster virus (VZV) Various tissues VZV reactivation
JC virus CSF Progressive multifocal leukoencephalopathy
Enterovirus CSF Aseptic meningitis
Parvovirus B19 Amniotic fluid
Serum Hydrops fetalis
Adenovirus Urine
Blood Immunocompromised patients, transplant recipients
Ehrlichia Blood Human granulocytic and monocytic ehrlichiosis
Bordetella pertussis Nasopharyngeal aspirate Whooping cough
Legionella pneumophila Respiratory Atypical pneumonia
Chlamydia pneumoniae Respiratory Atypical pneumonia
Mycoplasma pneumoniae Respiratory Atypical pneumonia
Helicobacter pylori Gastric fluid
Stool Peptic ulcer disease

aAll tests use polymerase chain reaction. The list is not all-inclusive.

Main Article