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Volume 7, Number 3—June 2001


Melioidosis: An Emerging Infection in Taiwan?

Po-Ren Hsueh*, Lee-Jene Teng*, Li-Na Lee*†, Cheong-Ren Yu*, Pan-Chyr Yang*, Shen-Wu Ho*†, and Kwen-Tay Luh*Comments to Author 
Author affiliations: *National Taiwan University Hospital, Taipei, Taiwan; †National Taiwan University College of Medicine, Taipei, Taiwan

Main Article

Table 1

Clinical characteristics of 15 patients in Taiwan with invasive infections caused by Burkholderia pseudomallei

no./ref Age/
sex Travel
history Underlying diseases/associated
conditions Clinical
diagnosis Isolate
source (date) Treatment Out-come
1 (13) 46/M Philippines Near drowning Cavitary pneumonia Blood (9/82) Cephalothin, amikacin (30 d) Surv
2 (14) 75/F None Liver cirrhosis, uremia, DM Pneumonia, peritoni-tis Blood, ascites (8/94) Cefazolin, gentamicin (1 d) Died
3 (14) 70/M None None Pneumonia Blood (8/94) Ceftazidime (30 d), amoxicillin-clavulanate (3 mo) Surv
4 (15) 70/M China None Mycotic aneurysm Blood (11/94); aortic tissue (12/94) Ceftazidime (35 d); amoxicillin-clavulanate (6 mo) Surv
5 (16) 75/M None DM Pneumonia Blood (11/96) Ceftazidime (14 d); amoxicillin-clavulanate (2 mo ) Surv
6 (17) 51/M Burma DM Pneumonia, adrenal gland abscess Blood (7/97) Ceftazidime (2 d);cotrimoxazole (60 d) Surv
7 (18) 40/M None DM Pneumonia, ARDS Blood (7/97) Moxalactam 9 d); netilmicin (9 d); erythromycin (9 d) Died
8 (PR) 56/M Thailand None Pneumonia Blood-A (11/96) Ceftazidime, gentamicin (1 d) Died
9 (PR) 67/M None COPD Pneumonia Blood-B (1/97) Ceftazidime (14 d); amoxicillin-clavulanate (2 mo) Surv
10 (PR) 73/M None Prostate cancer with bone metastasis; DM; cyproterone and leuprolide acetate use Cavitary pneumonia Lung aspirate -C1 (7/97); sputum-C2 (7/97) Ciprofloxacin (5 mo) Surv
11 (PR) 76/F None None Septic arthritis, subcutaneous abscess Blood-D1; blood-D2; synovial fluid-D3; abscess fluid-D4; wound drainage -D5; all 9/98 Ciprofloxacin (4 mo); surgical drainage Surv
12 (PR) 58/M None None Subcutaneous abscess Abscess fluid-E1 (4/99); abscess fluid-E2 (2/2000) Piperacillin (10 d); ciprofloxacin (14 d) Surv
13 (PR) 66/M None DM Pneumonia, septic arthritis, subcutaneous abscess Lung aspirate -F1 (5/99); synovial fluid-F2 (5/99); abscess aspirate -F3 (1/2000) Imipenem (10 d); ciprofloxacin (2 mo); meropenem (1 mo); amoxicillin-clavulanate (4 mo) Surv
14 (PR) 74/M None COPD Pneumonia Blood-G (9/99) Ceftazidime, amikacin (14 mo); ciprofloxacin (2 mo) Surv
15 (PR) 70/M None COPD, TB Pneumonia, empyema, ARDS Blood-H1 Blood-H2 (1/2000) Ceftazidime, amikacin (1 mo) Died

Abbreviations used in this table: ARDS, adult respiratory distress syndrome; COPD, chronic obstructive pulmonary disease; d, day; DM, diabetes mellitus; mo, month; PR, present report; surv, survived.

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