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Volume 7, Number 5—October 2001

Mycobacterium tuberculosis Beijing Genotype Strains Associated with Febrile Response to Treatment

Reinout van Crevel*Comments to Author , Ron H.H. Nelwan†, Wilma de Lenne*, Yelilsan Veeraragu‡, Adri G. van der Zanden§, Zulkifli Amin†, Jos W.M. van der Meer*, and Dick van Soolingen¶
Author affiliations: *University Medical Center Nijmegen, Nijmegen, the Netherlands; †University of Indonesia, Jakarta, Indonesia; ‡Trisakti University, Jakarta, Indonesia; §Gelre Hospitals, Apeldoorn, the Netherlands; ¶National Institute of Public Health and the Environment (RIVM), Bilthoven, the Netherlands

Main Article


Drug resistance and patient characteristics by Mycbacterium tuberculosis genotype, Indonesia

Patient characteristics Beijing, n=31 (%) Other, n=61(%)
Male 19 (61) 35 (57)
Age in years, median (range) 31 (19-68) 29 (17-70)
BCG scar 8 (26) 14 (23)
Chest X-ray
cavities 16 (52) 29/55a (53)
bilateral disease 24 (77) 40/55 (73)
Febrile response to treatentb 15 (48) 13 (21)
Patient strain resistant toc n = 27 (%) n = 56 (%)
Isoniazid 10 (37) 11 (20)
Rifampicin 2 (7) 2 (4)
Pyrazinamide 0 3 (5)
Ethambutol 1 (4) 3 (5)
Streptomycin 4 (15) 3 (5)
Any prescribed drug 11 (39) 14 (25)

aSix chest X-rays in the non-Beijing group were evaluated by only one pulmonologist.
bSignificant difference between groups (Mann-Whitney U-test; p=0.02).
c Eighty-three isolates were available for drug susceptibility testing.

Main Article

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Page updated: April 26, 2012
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