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Volume 8, Number 1—January 2002


Nosocomial Endocarditis Caused by Corynebacterium amycolatum and Other Nondiphtheriae Corynebacteria

Karen L. Knox*Comments to Author  and Alison H. Holmes†
Author affiliations: *St. George’s Hospital, London, United Kingdom; †Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom

Main Article

Table 1

Patient characteristics, heart valve affected, source of Corynebacterium infection and organism cultured, London

Case Age(y)/sex Underlying disease process Site of endocarditis Associated IIDa Therapy Outcome
1 74/F ANCA +
vasculitis Native mitral valve Vascular catheter
for HD Vancomycin i.v. + oral rifampicin,
16 monthsb Resolved
at 21 months
2 69/F ANCA +
vasculitis Native
mitral valve Gortex AV fistula,
vascular catheter
for HD Vancomycin i.v. + oral
37 days;
mitral valve replacement Died of unrelated
causes 9 weeks after diagnosis
3 53/M Postoperative
acute renal
failure Prosthetic
mitral valve
(Starr Edwards) Vascular catheter
for HD
CVC Vancomycin i.v. + oral
42 days Died of unrelated
causes 8.5 months postdiagnosis

aPatient refused surgery and follow-up echocardiograms.

bIID = indwelling intravascular device; ANCA = anti-neutrophil cytoplasmic antibody; HD = hemodialysis; AV = arteriovenous; CVC = central venous catheter.

Main Article