Volume 8, Number 1—January 2002
Dispatch
Nosocomial Endocarditis Caused by Corynebacterium amycolatum and Other Nondiphtheriae Corynebacteria
Karen L. Knox*
and Alison H. Holmes†
and Alison H. Holmes†
Table 1
Patient characteristics, heart valve affected, source of Corynebacterium infection and organism cultured, London
| Case | Age(y)/sex | Underlying disease process | Site of endocarditis | Associated IIDa | Therapy | Outcome |
|---|---|---|---|---|---|---|
| 1 | 74/F | ANCA + vasculitis | Native mitral valve | Vascular catheter for HD | Vancomycin i.v. + oral rifampicin, 16 monthsb | Resolved at 21 months postdiagnosis |
| 2 | 69/F | ANCA + vasculitis | Native mitral valve | Gortex AV fistula, vascular catheter for HD | Vancomycin i.v. + oral rifampicin, 37 days; mitral valve replacement | Died of unrelated causes 9 weeks after diagnosis |
| 3 | 53/M | Postoperative acute renal failure | Prosthetic mitral valve (Starr Edwards) | Vascular catheter for HD CVC | Vancomycin i.v. + oral rifampicin, 42 days | Died of unrelated causes 8.5 months postdiagnosis |
aPatient refused surgery and follow-up echocardiograms.
bIID = indwelling intravascular device; ANCA = anti-neutrophil cytoplasmic antibody; HD = hemodialysis; AV = arteriovenous; CVC = central venous catheter.
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