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Volume 8, Number 3—March 2002
Synopsis

Human Campylobacteriosis in Developing Countries1

Akitoye O. Coker*Comments to Author , Raphael D. Isokpehi*, Bolaji N. Thomas*, Kehinde O. Amisu*, and C. Larry Obi†
Author affiliations: *University of Lagos, Idi-Araba, Lagos, Nigeria; †University of Venda for Science and Technology, Thohoyandon, South Africa;

Main Article

Table 3

Distribution of Campylobacter jejuni and C. coli biotypes and serotypes in three African countries

Countries (ref.) Biotypes Serotypes
C. jejuni C. coli
I II III IV I II
Nigeria (33) 52.5 28.7 - - 9.9 8.9 1, 8, 11, 20, 28, 45
Central African Republic (34) 31.9 11.0 2.4 - 44.0 11.5 -
South Africa (35) 95.4 1.5 - - 3.1 4, 2, 12, 19, 23, 36

Main Article

References
  1. Nachamkin  I, Blaser  MJ. Campylobacter, 2nd edition. Washington: American Society for Microbiology; 2000.
  2. Altekruse  SF, Stern  NJ, Fields  PI, Swerdlow  DL. Campylobacter jejuni--an emerging foodborne pathogen. Emerg Infect Dis. 1999;5:2835.PubMedGoogle Scholar
  3. Tropical disease research: progress 1999-2000. Fifteenth Programme report of the UNDP/World Bank/WHO Special Programme for Research & Training in Tropical Diseases. (TDR/GEN/01.5). Geneva: World Health Organization; 2001.
  4. Lambrechts  T, Bryce  J, Orinda  V. Integrated management of childhood illness: a summary of first experiences. Bull World Health Organ. 1999;77:58294.PubMedGoogle Scholar
  5. Taylor  DN. Campylobacter infections in developing countries. In: Nachamkin I, Blaser MJ, Tompkins LS, editors. Campylobacter jejuni: Current status and future trends. Washington: American Society for Microbiology; 1992. p.20-30.
  6. Oberhelman  RA, Taylor  DN. Campylobacter infections in developing countries. In: Nachamkin I, Blaser MJ, editors. Campylobacter, 2nd edition. Washington: American Society for Microbiology; 2000. p.139-53.
  7. Coker  AO, Isokpehi  RD, Thomas  BN, Amisu  KO. International collaboration on campylobacters: Experience from Lagos, Nigeria. [Abstract S-05]. In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):168.
  8. Tauxe  RV. Epidemiology of Campylobacter jejuni infections in the United States and other industrialized nations. In: Nachamkin I, Blaser MJ, Tompkins LS, editors. Campylobacter jejuni: Current and future trends. Washington: American Society for Microbiology; 1992. p.9-12.
  9. de Wit  MAS, Koopmans  MPG, Kortbeek  LM, van Leeuwen  NJ, Bartelds  AIM, van Duynhoven  YTHP. Gastroenteritis in sentinel general practices, the Netherlands. Emerg Infect Dis. 2001;7:8291.PubMedGoogle Scholar
  10. Engberg  J, Aarestrup  FM, Taylor  DE, Gerner-Smidt  P, Nachamkin  I. Quinolone and macrolide resistance in Campylobacter jejuni and C. coli: resistance and trends in human isolates. Emerg Infect Dis. 2001;7:2434.PubMedGoogle Scholar
  11. Frost  JA. Current epidemiological issues in human campylobacteriosis. J Appl Microbiol. 2001;90(Suppl):85S95S. DOIGoogle Scholar
  12. Rao  MR, Naficy  AB, Savarino  SJ, Abu-Elyazeed  R, Wierzba  TF, Peruski  LF, Pathogenicity and convalescent excretion of Campylobacter in rural Egyptian children. Am J Epidemiol. 2001;154:16673. DOIPubMedGoogle Scholar
  13. Wren  BW, Linton  D, Dorrell  N, Karlyshev  AV. Post genome analysis of Campylobacter jejuni. J Appl Microbiol. 2001;90(Suppl):36S44S. DOIGoogle Scholar
  14. Megraud  F, Boudraa  G, Bessaoud  K, Bensid  S, Dabis  F, Soltana  R, Incidence of Campylobacter infection in infants in western Algeria and the possible protective role of breast feeding. Epidemiol Infect. 1990;105:738.PubMedGoogle Scholar
  15. Koulla-Shiro  S, Loe  C, Ekoe  T. Prevalence of Campylobacter enteritis in children from Yaounde (Cameroon). Cent Afr J Med. 1995;41:914.PubMedGoogle Scholar
  16. Gedlu  E, Aseffa  A. Campylobacter enteritis among children in north-west Ethiopia: a 1-year prospective study. Ann Trop Paediatr. 1996;16:20712.PubMedGoogle Scholar
  17. Coker  AO, Adefeso  AO. The changing patterns of Campylobacter jejuni/coli in Lagos, Nigeria after ten years. East Afr Med J. 1994;71:43740.PubMedGoogle Scholar
  18. Lindblom  GB, Ahren  C, Changalucha  J, Gabone  R, Kaijser  B, Nilsson  LA, Campylobacter jejuni/coli and enterotoxigenic Escherichia coli (ETEC) in faeces from children and adults in Tanzania. Scand J Infect Dis. 1995;27:58993. DOIPubMedGoogle Scholar
  19. Simango  C, Nyahanana  M. Campylobacter enteritis in children in an urban community. Cent Afr Med J. 1997;43:1725.
  20. Mangia  AH, Duarte  AN, Duarte  R, Silva  LA, Bravo  VL, Leal  MC. Aetiology of acute diarrhoea in hospitalized children in Rio de Janeiro City, Brazil. J Trop Pediatr. 1993;39:3657.PubMedGoogle Scholar
  21. Ramiro Cruz  J, Cano  F, Bartlett  AV, Mendez  H. Infection, diarrhea, and dysentery caused by Shigella species and Campylobacter jejuni among Guatemalan rural children. Pediatr Infect Dis J. 1994;13:21623.PubMedGoogle Scholar
  22. Na'was  TE, Abo-Shehada  MN. A study of the bacterial and parasitic causes of acute diarrhoea in northern Jordan. J Diarrhoeal Dis Res. 1991;9:3059.PubMedGoogle Scholar
  23. Albert  MJ, Faruque  AS, Faruque  SM, Sack  RB, Mahalanabis  D. Case-control study of enteropathogens associated with childhood diarrhea in Dhaka, Bangladesh. J Clin Microbiol. 1999;37:345864.PubMedGoogle Scholar
  24. Echeverria  P, Taylor  DN, Lexsomboon  U, Bhaibulaya  M, Blacklow  NR, Tamura  K, Case-control study of endemic diarrheal disease in Thai children. J Infect Dis. 1989;159:5438.PubMedGoogle Scholar
  25. Yamashiro  T, Nakasone  N, Higa  N, Iwanaga  M, Insisiengmay  S, Phounane  T, Etiological study of diarrheal patients in Vientiane, Lao People's Democratic Republic. J Clin Microbiol. 1998;36:21959.PubMedGoogle Scholar
  26. van Koningsveld  R, Rico  R, Gerstenbluth  I, Schmitz  PI, Ang  CW, Merkies  IS, Gastroenteritis-associated Guillain-Barré syndrome on the Caribbean island Curacao. Neurology. 2001;56:146772.PubMedGoogle Scholar
  27. Desheng  L, Zhixin  C, Bolun  W. Age distribution of diarrhoeal and healthy children infected with Campylobacter jejuni. J Trop Med Hyg. 1992;95:21820.PubMedGoogle Scholar
  28. Taylor  DN, Perlman  DM, Echeverria  PD, Lexomboon  U, Blaser  MJ. Campylobacter immunity and quantitative excretion rates in Thai children. J Infect Dis. 1993;168:7548.PubMedGoogle Scholar
  29. Haq  JA, Rahman  KM. Campylobacter jejuni as a cause of acute diarrhoea in children: a study at an urban hospital in Bangladesh. J Trop Med Hyg. 1991;94:504.PubMedGoogle Scholar
  30. Bichile  LS, Saraswati  K, Popat  UR, Nanivadekar  SA, Deodhar  LP. Acute Campylobacter jejuni enteritis in 385 hospitalised patients. J Assoc Physicians India. 1992;40:1646.PubMedGoogle Scholar
  31. Bhadra  RK, Lior  H, Misra  SK, Pal  SC, Nair  GB. Serotypes & biotypes of Campylobacter jejuni & C. coli from diverse sources in Calcutta. Indian J Med Res. 1989;89:2258.PubMedGoogle Scholar
  32. Nath  G, Shukla  BN, Reddy  DC, Sanyal  SC. A community study on the aetiology of childhood diarrhoea with special reference to Campylobacter jejuni in a semiurban slum of Varanasi, India. J Diarrhoeal Dis Res. 1993;11:1658.PubMedGoogle Scholar
  33. Alabi  SA, Coker  AO, Dosunmu-Ogunbi  O, Odugbemi  T. Biotype and serogroup distribution of Campylobacter isolates from children in Nigeria. J Clin Microbiol. 1986;24:8568.PubMedGoogle Scholar
  34. Georges-Courbot  MC, Gouandjika  I, Martin  PM, Georges  AJ. Biotype and Lior serogroup distribution of enteric Campylobacter isolated from children in Bangui (Central African Republic), and comparison with Penner serotypes. Res Microbiol. 1989;140:48997. DOIPubMedGoogle Scholar
  35. Lastovica  AJ, le Roux  E, Congi  RV, Penner  JL. Distribution of sero-biotypes of Campylobacter jejuni and C. coli isolated from paediatric patients. J Med Microbiol. 1986;21:15.PubMedGoogle Scholar
  36. Adegbola  RA, Alabi  SA, Akinkuade  FO, Coker  AO, Odugbemi  T. Correlation between human and animal bio-serogroups of Campylobacter isolates in Nigeria. J Trop Med Hyg. 1990;93:2803.PubMedGoogle Scholar
  37. Smith  SI, Olukoya  DK, Fox  AJ, Coker  AO. Deoxyribonucleic acid restriction digest patterns in Campylobacter species: a comparison with Penner serotype. Br J Biomed Sci. 2000;57:13741.PubMedGoogle Scholar
  38. Vandenberg  O, Dediste  A, Vlaes  L, Ebraert  A, Retore  P, Douat  N, Prevalence and clinical features of non jejuni/coli Campylobacter species and related organisms in stool specimens. [Abstract P-22]. In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291(Suppl 31):144.
  39. le Roux  E, Lastovica  AJ. The Cape Town Protocol: how to isolate the most campylobacters for your dollar, pound, franc, yen, etc. In: Lastovica AJ, Newell DG, Lastovica EE, editors. Proceedings of the 9th International Workshop on Campylobacter, Helicobacter and Related Organisms, Cape Town, South Africa Sept 15-19 1997. Cape Town: Institute of Child Health; 1998. p. 30-33.
  40. Amisu  KO, Coker  AO, Isokpehi  RD. First isolation of aerotolerant Campylobacter (Arcobacter) strains in Nigeria. [Abstract P-18] In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):143.
  41. Steinbrückner  B, Ruberg  F, Vetter-Knoll  M, Kist  M. Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli isolated in Freiburg from 1992 to 2000. [Abstract B-12] In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):8.
  42. Feierl  G, Wagner  U, Sixl  B, Grisold  A, Daghofer  E, Marth  E. Epidemiology of campylobacteriosis and development of resistance in Styria, Austria. [Abstract B-15]. In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):9.
  43. Hoge  CW, Gambel  JM, Srijan  A, Pitarangsi  C, Echeverria  P. Trends in antibiotic resistance among diarrheal pathogens isolated in Thailand over 15 years. Clin Infect Dis. 1998;26:3415. DOIPubMedGoogle Scholar
  44. Wickin  HV, Thwaites  RT, Frost  JA. Drug resistance in Campylobacter species in England and Wales, 1993-2001. [Abstract B-05] In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001; 291 (Suppl 31):6.
  45. Nachamkin  I, Ung  H, Li  M. Fluoroquinolone resistant Campylobacter jejuni in Philadelphia, 1982-2000. [Abstract B-06]. In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):6.
  46. Melby  KK, Mannsåker  T. Antibiotic sensitivity pattern of Campylobacter spp recovered over a ten year period from patients residing in Oslo Area. [Abstract B-17]. In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):9.
  47. Gallardo  F, Gascon  J, Ruiz  J, Corachan  M, Jimenez de Anta  M, Vila  J. Campylobacter jejuni as a cause of traveler's diarrhea: clinical features and antimicrobial susceptibility. J Travel Med. 1998;5:236. DOIPubMedGoogle Scholar
  48. Shlim  DR, Hoge  CW, Rajah  R, Scott  RM, Pandy  P, Echeverria  P. Persistent high risk of diarrhea among foreigners in Nepal during the first 2 years of residence. Clin Infect Dis. 1999;29:6136. DOIPubMedGoogle Scholar
  49. Smith  KE, Besser  JM, Hedberg  CW, Leano  FT, Bender  JB, Wicklund  JH, Quinolone-resistant Campylobacter jejuni infections in Minnesota, 1992-1998. N Engl J Med. 1999;340:152532. DOIPubMedGoogle Scholar
  50. Mattila  L, Siitonen  A, Kyronseppa  H, Simula  I, Oksanen  P, Stenvik  M, Seasonal variation in etiology of travelers' diarrhea. Finnish-Moroccan Study Group. J Infect Dis. 1992;165:3858.PubMedGoogle Scholar
  51. Coker  AO, Dosunmu-Ogunbi  O. Gastroenteritis due to Campylobacter jejuni in Lagos, Nigeria. Cent Afr J Med. 1985;31:724.PubMedGoogle Scholar
  52. Nachamkin  I, Allos  BM, Ho  T. Campylobacter species and Guillain-Barré syndrome. Clin Microbiol Rev. 1998;11:55567.PubMedGoogle Scholar
  53. Ho  TW, Mishu  B, Li  CY, Gao  CY, Cornblath  DR, Griffin  JW, Guillain-Barré syndrome in northern China. Relationship to Campylobacter jejuni infection and anti-glycolipid antibodies. Brain. 1995;118:597605. DOIPubMedGoogle Scholar
  54. Hariharan  H, Naseema  K, Kumaran  C, Shanmugam  J, Nair  MD, Radhakrishnan  K. Detection of Campylobacter jejuni/C. coli infection in patients with Guillain-Barré syndrome by serology and culture. New Microbiol. 1996;19:26771.PubMedGoogle Scholar
  55. Lastovica  AJ, Goddard  EA, Argent  AC. Guillain-Barré syndrome in South Africa associated with Campylobacter jejuni O:41 strains. J Infect Dis. 1997;176(Suppl 2):S13943. DOIPubMedGoogle Scholar
  56. Wassenaar  TM, Fry  BN, Lastovica  AJ, Wagenaar  JA, Coloe  PJ, Duim  B. Genetic characterization of Campylobacter jejuni O:41 isolates in relation with Guillain-Barre syndrome. J Clin Microbiol. 2000;38:8746.PubMedGoogle Scholar
  57. Quinn  TC. Diversity of Campylobacter species and its impact on patients infected with human immunodeficiency virus. Clin Infect Dis. 1997;24:11147. DOIPubMedGoogle Scholar
  58. Lastovica  AJ, Mitchie  C, Maartens  G. Campylobacter infection in HIV+ South African children and adults. [Abstract Q-01]. In: Hacker J, editor. Abstracts of scientific presentations of the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, Freiburg, Germany, Sept 1-5, 2001. Int J Med Microbiol 2001;291 (Suppl 31):151.
  59. Germani  Y, Minssart  P, Vohito  M, Yassibanda  S, Glaziou  P, Hocquet  D, Etiologies of acute, persistent, and dysenteric diarrheas in adults in Bangui, Central African Republic, in relation to human immunodeficiency virus serostatus. Am J Trop Med Hyg. 1998;59:100814.PubMedGoogle Scholar
  60. Adetunji  J. Trends in under-5 mortality rates and the HIV/AIDS epidemic. Bull World Health Organ. 2000;78:12006.PubMedGoogle Scholar
  61. Blaser  MJ, Black  RE, Duncan  DJ, Amer  J. Campylobacter jejuni-specific serum antibodies are elevated in healthy Bangladeshi children. J Clin Microbiol. 1985;21:1647.PubMedGoogle Scholar
  62. Blaser  MJ, Taylor  DN, Echeverria  P. Immune response to Campylobacter jejuni in a rural community in Thailand. J Infect Dis. 1986;153:24954.PubMedGoogle Scholar
  63. Martin  PM, Mathiot  J, Ipero  J, Kirimat  M, Georges  AJ, Georges-Courbot  MC. Immune response to Campylobacter jejuni and Campylobacter coli in a cohort of children from birth to 2 years of age. J Clin Microbiol. 1989;57:25426.
  64. Blaser  MJ. Epidemiologic and clinical features of Campylobacter jejuni infections. J Infect Dis. 1997;176(Suppl. 2):S1035. DOIPubMedGoogle Scholar
  65. Obi  CL, Coker  AO. Campylobacter jejuni antibody in patients with diarrhoea and asymptomatic individuals in Lagos, Nigeria. Cent Afr J Med. 1989;66:2769.
  66. Taylor  DN, Echeverria  P, Pitarangsi  C, Seriwatana  J, Bodhidatta  L, Blaser  MJ. Influence of strain characteristics and immunity on the epidemiology of Campylobacter infections in Thailand. J Clin Microbiol. 1988;26:8638.PubMedGoogle Scholar
  67. Ruiz-Palacious  GM, Calva  JJ, Pickering  LK, Lopez-Vidal  Y, Volkow  P, Pezzarossi  H, Protection of breast-fed infants against Campylobacter diarrhea by antibodies in human milk. J Pediatr. 1990;116:70713. DOIPubMedGoogle Scholar
  68. Calva  JJ, Ruiz-Palacious  GM, Lopez-Vidal  AB, Ramos  A, Bojalil  R. Cohort study of intestinal infection with Campylobacter in Mexican children. Lancet. 1988;I:5036. DOIGoogle Scholar
  69. Coker  AO, Isokpehi  RD, Thomas  BN, Fagbenro-Beyioku  AF, Omilabu  SA. Zoonotic infections in Nigeria: overview from a medical perspective. Acta Trop. 2000;76:5963. DOIPubMedGoogle Scholar
  70. Raji  MA, Adekeye  JO, Kwaga  JK, Bale  JO. Bioserogroups of Campylobacter species isolated from sheep in Kaduna State, Nigeria. Small Rumin Res. 2000;37:21521. DOIPubMedGoogle Scholar
  71. Pattison  M. Practical intervention strategies for Campylobacter. J Appl Microbiol. 2001;90(Suppl):121S5S. DOIGoogle Scholar
  72. Rasrinaul  L, Suthienkul  O, Echeverria  PD, Taylor  DN, Seriwatana  J, Bangtrakulnonth  A, Foods as a source of enteropathogens causing childhood diarrhea in Thailand. Am J Trop Med Hyg. 1988;39:97102.PubMedGoogle Scholar
  73. Osano  O, Arimi  SM. Retail poultry and beef as sources of Campylobacter jejuni. East Afr Med J. 1999;76:1413.PubMedGoogle Scholar
  74. Quinones-Ramirez  EI, Vazquez-Salinas  C, Rodas-Suarez  OR, Ramos-Flores  MO, Rodriguez-Montano  R. Frequency of isolation of Campylobacter from roasted chicken samples from Mexico City. J Food Prot. 2000;63:1179.PubMedGoogle Scholar
  75. Murray  CJL, Lopez  AD, eds. The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. (Global Burden of Disease and Injury Series, Vol. I). Cambridge (MA): Harvard School of Public Health on behalf of the World Health Organization and the World Bank; 1996.
  76. Havelaar  AH, de Wit  MA, van Koningsveld  R, van Kempen  E. Health burden in the Netherlands due to infection with thermophilic Campylobacter spp. Epidemiol Infect. 2000;125:50522. DOIPubMedGoogle Scholar

Main Article

1 Portions of this review were presented at the World Health Organization Consultation on the Increasing Incidence of Campylobacteriosis in Humans, Copenhagen, Denmark, November 1-25, 2000. In addition, relevant emerging information from the 11th International Workshop on Campylobacter, Helicobacter and Related Organisms, held in Freiburg, Germany, September 1-5, 2001, are included.

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Page updated: July 15, 2010
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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