Volume 8, Number 3—March 2002
Research
Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis
Robert B. Tesh
, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao
, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao
Table 6
Serologic response of hamsters following immunization with the 17D yellow fever (YF) vaccine and subsequent challenge with West Nile virus (WNV)
| Hamster no. | HI antibody titer 30 days after YF immunization | HI antibody titer 6 days after WNV challenge | WN MAC-ELISA 6 days after WNV challenge | ||
|---|---|---|---|---|---|
| YF | WNV | YF | WNV | ||
| 8226 | 1:20 | 1:20 | 1:320 | 1:320 | 0.783a |
| 8227 | 1:40 | 1:20 | 1:320 | 1:320 | 0.484 |
| 8228 | 1:80 | 1:40 | 1:640 | 1:640 | 0.378 |
| 8229 | <1:20 | 1:20 | 1:640 | 1:640 | 0.311 |
| 8230 | <1:20 | 1:20 | 1:320 | 1:320 | 0.694 |
| 8231 | 1:40 | 1:20 | 1:640 | 1:640 | 0.511 |
| 8233 | 1:40 | 1:20 | 1:320 | 1:320 | 0.345 |
| 8234 | 1:20 | 1:20 | 1:640 | 1:640 | 0.418 |
| 8235 | 1:40 | 1:40 | 1:320 | 1:320 | 0.658 |
aOptical density value (>0.200 is positive).
HI = hemagglutination inhibition.
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