Volume 8, Number 3—March 2002
Research
Immunization with Heterologous Flaviviruses Protective Against Fatal West Nile Encephalitis
Robert B. Tesh
, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao
, Amelia P.A. Travassos da Rosa, Hilda Guzman, Tais P. Araujo, and Shu-Yuan Xiao
Table 4
Serologic response of hamsters following immunization with the SA14-2-8 vaccine strain of Japanese encephalitis virus (JEV) and subsequent challenge with West Nile virus (WNV)
| Hamster no. | HI antibody 30 days after JEV immunization | HI antibody 6 days after WNV challenge | WN MAC-ELISA 6 days after WNV challenge | ||
|---|---|---|---|---|---|
| JEV | WNV | JEV | WNV | ||
| 8236 | 1:80 | 1:80 | 1:640 | 1:640 | 0.166a |
| 8237 | 1:40 | 1:80 | 1:320 | 1:320 | 0.205 |
| 8238 | 1:80 | 1:80 | 1:640 | 1:640 | 0.239 |
| 8239 | 1:80 | 1:80 | 1:640 | 1:640 | 0.173 |
| 8240 | 1:80 | 1:80 | 1:640 | 1:640 | 0.245 |
| 8241 | 1:80 | 1:80 | 1:320 | 1:640 | 0.271 |
| 8242 | 1:80 | 1:80 | 1:1,280 | 1:1,280 | 0.209 |
| 8243 | 1:40 | 1:80 | 1:160 | 1:160 | 0.205 |
| 8244 | 1:40 | 1:80 | 1:320 | 1:320 | 0.229 |
| 8245 | 1:80 | 1:80 | 1:160 | 1:160 | NT |
aOptical density value (³0.200 is positive).
HI = hemagglutination inhibition. NT = not tested.
Page created: July 15, 2010
Page updated: July 15, 2010
Page reviewed: July 15, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.