Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 8, Number 4—April 2002
Perspective

Feline Host Range of Canine parvovirus: Recent Emergence of New Antigenic Types in Cats

Yasuhiro Ikeda*†Comments to Author , Kazuya Nakamura†, Takayuki Miyazawa†, Yukinobu Tohya†, Eiji Takahashi†, and Masami Mochizuki‡
Author affiliations: *University College London, London, United Kingdom; †University of Tokyo, Bunkyo-ku, Tokyo, Japan; ‡Kyoritsu Shoji Corporation, Chiyoda-ku, Tokyo, Japan;

Main Article

Figure 1

Antigenic profile of feline parvoviruses, including Canine parvovirus 2c (CPV-2c) types. Subtype-specific monoclonal antibodies are used to type the viruses in a hemagglutinin-inhibition test (HI). Mink enteritis virus (MEV-3) shows similar patterns to MEV-2  (2). FPLV = Feline panleukopenia virus; BFPV = blue fox parvovirus.

Figure 1. Antigenic profile of feline parvoviruses, including Canine parvovirus 2c (CPV-2c) types. Subtype-specific monoclonal antibodies are used to type the viruses in a hemagglutinin-inhibition test (HI). Mink enteritis virus (MEV-3) shows similar patterns to MEV-2 (2). FPLV = Feline panleukopenia virus; BFPV = blue fox parvovirus.

Main Article

References
  1. Wills  GC. Notes on infectious enteritis of mink and its relationship to feline enteritis. Can J Comp Med. 1952;16:41920.PubMedGoogle Scholar
  2. Parrish  CR, Gorham  JR, Schwartz  TM, Carmichael  LE. Characterization of antigenic variation among mink enteritis virus isolates. Am J Vet Res. 1984;45:25919.PubMedGoogle Scholar
  3. Parrish  CR, Carmichael  LE. Antigenic structure and variation of canine parvovirus type-2, feline panleukopenia virus, and mink enteritis virus. Virology. 1983;129:40114. DOIPubMedGoogle Scholar
  4. Appel  MJ, Cooper  BJ, Greisen  H, Scott  F, Carmichael  LE. Canine viral enteritis. I. Status report on corona- and parvo-like viral enteritides. Cornell Vet. 1979;69:12333.PubMedGoogle Scholar
  5. Kelly  WR. An enteric disease of dogs resembling feline panleucopaenia. Aust Vet J. 1978;54:593. DOIPubMedGoogle Scholar
  6. Gumbrell  RC. Parvovirus infection in dogs. N Z Vet J. 1979;27:113.PubMedGoogle Scholar
  7. Kelly  WR, Atwell  RB. Diffuse subacute myocarditis of possible viral aetiology: a cause of sudden death in pups. Aust Vet J. 1979;55:367. DOIPubMedGoogle Scholar
  8. Kariatsumari  T, Horiuchi  M, Hama  E, Yaguchi  K, Ishigurio  N, Goto  H, Construction and nucleotide sequence analysis of an infectious DNA clone of the autonomous parvovirus, mink enteritis virus. J Gen Virol. 1991;72:86775. DOIPubMedGoogle Scholar
  9. Horiuchi  M, Yamaguchi  Y, Gojobori  T, Mochizuki  M, Nagasawa  H, Toyoda  Y, Differences in the evolutionary pattern of feline panleukopenia virus and canine parvovirus. Virology. 1998;249:44052. DOIPubMedGoogle Scholar
  10. Truyen  U, Geissler  K, Parrish  CR, Hermanns  W, Siegl  G. No evidence for a role of modified live virus vaccines in the emergence of canine parvovirus. J Gen Virol. 1998;79:11538.PubMedGoogle Scholar
  11. Ikeda  Y, Mochizuki  M, Naito  R, Nakamura  K, Miyazawa  T, Mikami  T, Predominance of canine parvovirus (CPV) in unvaccinated cat populations and emergence of new antigenic types of CPVs in cats. Virology. 2000;278:139. DOIPubMedGoogle Scholar
  12. Truyen  U, Gruenberg  A, Chang  SF, Obermaier  B, Veijalainen  P, Parrish  CR. Evolution of the feline-subgroup parvoviruses and the control of canine host range in vivo. J Virol. 1995;69:470210.PubMedGoogle Scholar
  13. Veijalainen  P. Characterization of biological and antigenic properties of raccoon dog and blue fox parvoviruses: a monoclonal antibody study. Vet Microbiol. 1988;16:21930. DOIPubMedGoogle Scholar
  14. Truyen  U, Muller  T, Heidrich  R, Tackmann  K, Carmichael  LE. Survey on viral pathogens in wild red foxes (Vulpes vulpes) in Germany with emphasis on parvoviruses and analysis of a DNA sequence from a red fox parvovirus. Epidemiol Infect. 1998;121:43340. DOIPubMedGoogle Scholar
  15. Parrish  CR. O onnell PH, Everman JF, Carmichael LE. Natural variation of canine parvovirus. Science. 1985;230:10468. DOIPubMedGoogle Scholar
  16. Strassheim  ML, Gruenberg  A, Veijalainen  P, Sgro  JY, Parrish  CR. Two dominant neutralizing antigenic determinants of canine parvovirus are found on the threefold spike of the virus capsid. Virology. 1994;198:17584. DOIPubMedGoogle Scholar
  17. Carlson  JH, Scott  FW. Feline panleukopenia. II. The relationship of intestinal mucosal cell proliferation rates to viral infection and development of lesions. Vet Pathol. 1977;14:17381.PubMedGoogle Scholar
  18. Johnson  RH, Margolis  G, Kilham  L. Identity of feline ataxia virus with feline panleucopenia virus. Nature. 1967;214:1757. DOIPubMedGoogle Scholar
  19. Kilham  L, Margolis  G, Colby  ED. Cerebellar ataxia and its congenital transmission in cats by feline panleukopenia virus. J Am Vet Med Assoc. 1971;158:888.PubMedGoogle Scholar
  20. Carpenter  JL. Feline panleukopenia: clinical signs and differential diagnosis. J Am Vet Med Assoc. 1971;158:8579.PubMedGoogle Scholar
  21. Robinson  WF, Wilcox  GE, Flower  RL, Smith  JR. Evidence for a parovirus as the aetiologic agent in the myocarditis of puppies. Aust Vet J. 1979;55:2945.PubMedGoogle Scholar
  22. Robinson  WF, Wilcox  GE, Flower  RL. Canine parvovirus disease: experimental reproduction of the enteric form with a parovirus isolated from a case of myocarditis. Vet Pathol. 1980;17:58999.PubMedGoogle Scholar
  23. Carlson  JH, Scott  FW, Duncan  JR. Feline panleukopenia. I. Pathogenesis in germfree and specific pathogen-free cats. Vet Pathol. 1977;14:7988.PubMedGoogle Scholar
  24. Goto  H, Hosokawa  S, Ichijo  S, Shimizu  K, Morohoshi  Y, Nakano  K. Experimental infection of feline panleukopenia virus in specific pathogen-free cats. Nippon Juigaku Zasshi. 1983;45:10912.PubMedGoogle Scholar
  25. Ikeda  Y, Shinozuka  J, Miyazawa  T, Kurosawa  K, Izumiya  Y, Nishimura  Y, Apoptosis in feline panleukopenia virus-infected lymphocytes. J Virol. 1998;72:69326.PubMedGoogle Scholar
  26. Truyen  U, Parrish  CR. Canine and feline host ranges of canine parvovirus and feline panleukopenia virus: distinct host cell tropisms of each virus in vitro and in vivo. J Virol. 1992;66:5399408.PubMedGoogle Scholar
  27. Horiuchi  M, Goto  H, Ishiguro  N, Shinagawa  M. Mapping of determinants of the host range for canine cells in the genome of canine parvovirus using canine parvovirus/mink enteritis virus chimeric viruses. J Gen Virol. 1994;75:131928. DOIPubMedGoogle Scholar
  28. Chang  SF, Sgro  JY, Parrish  CR. Multiple amino acids in the capsid structure of canine parvovirus co-ordinately determine the canine host range and specific antigenic and hemagglutination properties. J Virol. 1992;66:685867.PubMedGoogle Scholar
  29. Pollock  RV, Carmichael  LE. Use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus. Am J Vet Res. 1983;44:16975.PubMedGoogle Scholar
  30. Mochizuki  M, Harasawa  R, Nakatani  H. Antigenic and genomic variabilities among recently prevalent parvoviruses of canine and feline origin in Japan. Vet Microbiol. 1993;38:110. DOIPubMedGoogle Scholar
  31. Goto  H, Hirano  T, Uchida  E, Watanabe  K, Shinagawa  M, Ichijo  S, Comparative studies of physicochemical and biological properties between canine parvovirus and feline panleukopenia virus. Nippon Juigaku Zasshi. 1984;46:51926.PubMedGoogle Scholar
  32. Truyen  U, Agbandje  M, Parrish  CR. Characterization of the feline host range and a specific epitope of feline panleukopenia virus. Virology. 1994;200:494503. DOIPubMedGoogle Scholar
  33. Truyen  U, Evermann  JF, Vieler  E, Parrish  CR. Evolution of canine parvovirus involved loss and gain of feline host range. Virology. 1996;215:1869. DOIPubMedGoogle Scholar
  34. Steinel  A, Munson  L, van Vuuren  M, Truyen  U. Genetic characterization of feline parvovirus sequences from various carnivores. J Gen Virol. 2000;81:34550.PubMedGoogle Scholar
  35. Ikeda  Y, Miyazawa  T, Nakamura  K, Naito  R, Inoshima  Y, Tung  KC, Serosurvey for selected virus infections of wild carnivores in Taiwan and Vietnam. J Wildl Dis. 1999;35:57881.PubMedGoogle Scholar
  36. Mochizuki  M, Horiuchi  M, Hiragi  H, San Gabriel  MC, Yasuda  N, Uno  T. Isolation of canine parvovirus from a cat manifesting clinical signs of feline panleukopenia. J Clin Microbiol. 1996;34:21015.PubMedGoogle Scholar
  37. Chalmers  WS, Truyen  U, Greenwood  NM, Baxendale  W. Efficacy of feline panleucopenia vaccine to prevent infection with an isolate of CPV2b obtained from a cat. Vet Microbiol. 1999;69:415. DOIPubMedGoogle Scholar
  38. Nakamura  K, Sakamoto  M, Ikeda  Y, Sato  E, Kawakami  K, Miyazawa  T, Pathogenic potential of canine parovirus types 2a and 2c in domestic cats. Clin Diagn Lab Immunol. 2001;8:6638.PubMedGoogle Scholar
  39. Miyazawa  T, Ikeda  Y, Nakamura  K, Naito  R, Mochizuki  M, Tohya  Y, Isolation of feline parvovirus from peripheral blood mononuclear cells of cats in northern Vietnam. Microbiol Immunol. 1999;43:60912.PubMedGoogle Scholar
  40. Nakamura  K, Ikeda  Y, Miyazawa  T, Tohya  Y, Takahashi  E, Mochizuki  M. Characterization of cross reactivity of virus neutralizing antibodies induced by feline panleukopenia virus and canine parvovirus. Res Vet Sci. 2001;71:21922. DOIPubMedGoogle Scholar

Main Article

Page created: July 15, 2010
Page updated: July 15, 2010
Page reviewed: July 15, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external