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Volume 8, Number 5—May 2002
Research

Trends in Fluoroquinolone (Ciprofloxacin) Resistance in Enterobacteriaceae from Bacteremias, England and Wales, 1990–1999

David M. Livermore*Comments to Author , Dorothy James*, Mark Reacher†, Catriona Graham*, Thomas Nichols*, Peter Stephens‡, Alan P. Johnson*, and Robert C. George*
Author affiliations: *Central Public Health Laboratory, London, United Kingdom; †Communicable Disease Surveillance Centre, London, United Kingdom; ‡IMS-HEALTH UK, Pinner, Middlesex, United Kingdom;

Main Article

Table 2

Distribution of reports of ciprofloxacin resistance for Enterobacteriaceae from bacteremia in hospitals, England and Wales, 1990–1999

1990 1991 1992 1993 1994 1995 1996 1997 1998 1999
Escherichia coli
No. labs reporting ciproR
 isolates 25 29 39 40 57 52 58 68 94 89
Labs contributing >10% of
ciproR total (n)a 1 0 0 0 0 0 0 0 0 0
% of all ciproR reports from
top three contributorsa 33 19 17 20 13 19 26 17 11 12
Klebsiella spp.
No. labs reporting ciproR
 isolates 23 48 38 42 42 47 42 36 57 50
Labs contributing >10% of
ciproR total (n)a - 0 1 0 0 1 2 2 1 0
% of all ciproR reports from
 top three contributorsa - 17 29 15 21 32 35 39 23 21
Enterobacter spp.
No. labs reporting ciproR
 isolates 10 19 36 27 37 30 35 33 39 58
Labs contributing >10% of
ciproR total (n)a - - 0 - 0 2 2 0 0 0
% of all ciproR reports from
top three contributorsa - - 28 - 22 32 30 22 22 16
Proteus mirabilis
No. labs reporting ciproR
 isolates 2 2 1 6 12 6 3 6 12 20
Labs contributing >10% of
ciproR total (n) a - - - - - - - - - -
% of all ciproR reports from
 top three contributorsa - - - - - - - - - -

aNot calculated if <30 resistant isolates.
Cipro, ciprofloxacin; R, resistant; labs, laboratories.

Main Article

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Page updated: July 15, 2010
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