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Volume 8, Number 5—May 2002


Genetic Variants of Ehrlichia phagocytophila1, Rhode Island and Connecticut

Robert F. Massung*, Michael J. Mauel†, Jessica H. Owens*, Nancy Allan*, Joshua W. Courtney*, Kirby C. Stafford‡, and Thomas N. Mather†Comments to Author 
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †University of Rhode Island, Kingston, Rhode Island, USA; ‡Connecticut Agricultural Experiment Station, New Haven, Connecticut, USA

Main Article

Table 2

Variation within nucleotide region 74 to 446 in 16s rRNA gene sequences obtained for Ehrlichia phagocytophila-human agent (EP-ha),a the Rhode Island variants, and E. equi

Position number
76 84 157 176 284 299
EP-ha A G A G C A
RI variant 1 Gb A A G C A
RI variant 2 A G A A T A
RI variant 3 A G G G C A
RI variant 4 A G A G C G
E. equi/CA human A A A G C A

a The number designations for the EP-ha 16S rDNA sequence correspond to those reported by Chen et al. (4). GenBank Accession No. U02521.
b Variant base paris are shown in bold.-

Main Article

1Since this study was conducted, new nomenclature (Anaplasma phagocytophila) has been proposed; see Dumler JS, Barbet AF, Bekker CP, Dasch GA, Palmer GH, Ray SC, et al. Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia, and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and ‘HGE agent’ as subjective synonyms of Ehrlichia pagocytophila. Int J Syst Evol Microbiol 2001;51:2145-65.