Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 9, Number 4—April 2003
Research

Molecular Epidemiology of Human Enterovirus 71 Strains and Recent Outbreaks in the Asia-Pacific Region: Comparative Analysis of the VP1 and VP4 Genes

Mary Jane Cardosa*Comments to Author , David Perera*, Betty A. Brown†, Doosung Cheon‡, Hung Ming Chan*, Kwai Peng Chan§, Haewol Cho‡, and Peter McMinn¶
Author affiliations: *Universiti Malaysia Sarawak, Sarawak, Malaysia; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡National Institute of Health, Seoul, Korea; §Singapore General Hospital, Singapore; ¶Telethon Institute for Child Health Research, Perth, Western Australia, Australia

Main Article

Figure 2

An overview of the genetic relationships of human enterovirus 71 (HEV71) strains isolated from 1970 through 2002. Unrooted cladogram shows the genogroup relationships of HEV71 based on an alignment of the partial VP4 gene (nucleotide positions 744–950) consensus sequences for genogroups B1, B2, B3, B4, C1, C2, and C3. The complete VP4 gene sequence of the prototype strain BrCr-CA-70 (30) was used as an outgroup in the analysis. The bootstrap values in 1,000 pseudoreplicates for major lineages wi

Figure 2. An overview of the genetic relationships of human enterovirus 71 (HEV71) strains isolated from 1970 through 2002. Unrooted cladogram shows the genogroup relationships of HEV71 based on an alignment of the partial VP4 gene (nucleotide positions 744–950) consensus sequences for genogroups B1, B2, B3, B4, C1, C2, and C3. The complete VP4 gene sequence of the prototype strain BrCr-CA-70 (30) was used as an outgroup in the analysis. The bootstrap values in 1,000 pseudoreplicates for major lineages within the dendrogram are shown as percentages. The marker denotes a measurement of relative phylogenetic distance.

Main Article

Page created: December 08, 2010
Page updated: December 08, 2010
Page reviewed: December 08, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external