Volume 9, Number 7—July 2003
Research
Amoeba-Resisting Bacteria and Ventilator-Associated Pneumonia
Bernard La Scola*, Ioanna Boyadjiev*†, Gilbert Greub*, Atieh Khamis*, Claude Martin†, and Didier Raoult*†
Table 6
Clinical characteristics of patients with or without seroconversion to one of the amoeba-associated bacteriaa
| Clinical characteristics | Seroconversion (N=12) | No seroconversion (N=18) | p value |
|---|---|---|---|
| Demographic data | |||
| Median age in y (IQR) | 35 (25–43) | 24 (21–52) | 0.85 |
| Male (%) | 10 (83.3) | 15 (83.3) | 1 |
| Risk and potential confounding factors | |||
| Underlying disease (%) | 2 (16.6) | 3 (16.6) | 1 |
| Circulation injury (%) | 9 (75) | 14 (77.8) | 1 |
| Median APACHE IIa score (IQR) | 21 (14–4) | 23 (16–34) | 0.12 |
| Intubation in ICU (%) | 8 (66.6) | 7 (38.9) | 0.26 |
| Median hospitalization days (IQR) | 25 (19–41) | 17 (10–23) | 0.094 |
| Median intubation duration in days (IQR) | 11 (7–20) | 11 (7–20) | 0.8 |
| Median number of serum samples (IQR) | 3 (3–5) | 3 (2–4) | 0.12 |
| Clinical data | |||
| VAP (%) | 10 (83.3) | 7 (38.9) | 0.026 |
| Unexplained VAP (%) | 6 (50) | 2 (11.1) | 0.034 |
| Fever > 38.5 °C (%) | 12 (100) | 17 (84.4) | 1 |
| Unexplained fever (%) | 7 (58.3) | 11 (39.3) | 0.27 |
| SIRS (%) | 12 (100) | 11 (61.1) | 0.024 |
| Unexplained SIRS (%) | 7 (58.3) | 3 (14.3) | 0.045 |
| Death (%) | 2 (16.7) | 8 (44.4) | 0.23 |
| Paraclinical data | |||
| Leukocytes > 12 g/L (%) | 12 (100) | 14 (77.8) | 0.13 |
| Platelets > 500 g/L (%) | 5 (41.7) | 6 (33.3) | 0.7 |
| PCR detection of ARB in BAL samples(%) | 2 (17) | 0 | 0.15 |
aIQR, interquartile range; VAP, ventilator-associated pneumonia; SIRS, Systemic Inflammatory Response Syndrome; APACHE II, Acute Physiology and Chronic Health Evaluation II; PCR, polymerase chain reaction; ARB, angiotensin receptor blockers; BAL, bronchoalveolar lavage samples; bold p values are those that are significant (<0.05).
Page created: December 22, 2010
Page updated: December 22, 2010
Page reviewed: December 22, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.