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Volume 9, Number 8—August 2003
Perspective

Detecting Bioterror Attacks by Screening Blood Donors: A Best-Case Analysis

Edward H. Kaplan*Comments to Author , Christopher A. Patton†, William P. FitzGerald†, and Lawrence M. Wein‡
Author affiliations: *Yale School of Management and Yale Medical School, New Haven, Connecticut, USA; †American Red Cross, Arlington, Virginia, USA; ‡Stanford University, Stanford, California, USA

Main Article

Table 1

Incubation periods from infection through symptoms for Centers for Disease Control category A agents

Agent Incubation time (days)
Bacillus anthracis
<7
Clostridium botulinum
0.5–1.5
Yersinia pestis
1–6
Smallpox virus
7–17
Francisella tularensis
3–5
Hemorrhagic fever viruses 2–21 (Ebola); 5–10 (Marburg)

Source (11).

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References
  1. O’Toole  T, Mair  M, Inglesby  TV. Shining light on “Dark Winter.”. Clin Infect Dis. 2002;34:97283. DOIPubMed
  2. Webb  GF, Blaser  MJ. Mailborne transmission of anthrax: modeling and implications. Proc Natl Acad Sci U S A. 2002;99:702732. DOIPubMed
  3. Kaplan  EH, Craft  DL, Wein  LM. Emergency response to a smallpox attack: the case for mass vaccination. Proc Natl Acad Sci U S A. 2002;99:1093540. DOIPubMed
  4. Wein  LM, Craft  DL, Kaplan  EH. Emergency response to an anthrax attack. Proc Natl Acad Sci U S A. 2003;100:434651. DOIPubMed
  5. Broad  WJ. White House debate on smallpox slows plan for wide vaccination. New York Times 2002 Oct. 13; 20.
  6. Obstacles to biodefence. Nature. 2002;419:1. DOIPubMed
  7. De  BK, Bragg  SL, Sanden  GN, Wilson  KE, Diem  LA, Marston  CK, A two-component direct fluorescent-antibody assay for rapid identification of Bacillus anthracis. Emerg Infect Dis. 2002;8:10605.PubMed
  8. Espy  MJ, Cockerill  FR III, Meyer  RF, Bowen  MD, Poland  GA, Hadfield  TL, Detection of smallpox virus DNA by LightCycler PCR. J Clin Microbiol. 2002;40:19858. DOIPubMed
  9. Berdal  BP, Mehl  R, Haaheim  H, Loksa  M, Grunow  R, Burans  J, Field detection of Francisella tularensis. Scand J Infect Dis. 2000;32:28791. DOIPubMed
  10. Neergard  L. Scientists work on smallpox medicines. Associated Press Online, June 2 2002. Available from: URL:http://www.lexis-nexis.com
  11. Centers for Disease Control and Prevention. Biological diseases/agents: category A. Atlanta (GA): The Centers; 2003. Available from: URL:http://www.bt.cdc.gov/agent/agentlist.asp\#categoryadiseases
  12. Report on blood collection and transfusion in the United States in 1999. Bethesda (MD): National Blood Data Resource Center; 2000.
  13. Cox  DR. Renewal theory. London: Methuen & Co. Ltd.; 1967.
  14. Anderson  RM, May  RM. Infectious diseases of humans: dynamics and control. New York: Oxford University Press; 1991.
  15. Gani  R, Leach  S. Transmission potential of smallpox in contemporary populations. Nature. 2001;414:74851. DOIPubMed

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Page updated: December 22, 2010
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