Volume 9, Number 8—August 2003
Perspective
Detecting Bioterror Attacks by Screening Blood Donors: A Best-Case Analysis
Table 1
Incubation periods from infection through symptoms for Centers for Disease Control category A agents
Agent | Incubation time (days) |
---|---|
Bacillus anthracis |
<7 |
Clostridium botulinum |
0.5–1.5 |
Yersinia pestis |
1–6 |
Smallpox virus |
7–17 |
Francisella tularensis |
3–5 |
Hemorrhagic fever viruses | 2–21 (Ebola); 5–10 (Marburg) |
Source (11).
References
- O’Toole T, Mair M, Inglesby TV. Shining light on “Dark Winter.”. Clin Infect Dis. 2002;34:972–83. DOIPubMedGoogle Scholar
- Webb GF, Blaser MJ. Mailborne transmission of anthrax: modeling and implications. Proc Natl Acad Sci U S A. 2002;99:7027–32. DOIPubMedGoogle Scholar
- Kaplan EH, Craft DL, Wein LM. Emergency response to a smallpox attack: the case for mass vaccination. Proc Natl Acad Sci U S A. 2002;99:10935–40. DOIPubMedGoogle Scholar
- Wein LM, Craft DL, Kaplan EH. Emergency response to an anthrax attack. Proc Natl Acad Sci U S A. 2003;100:4346–51. DOIPubMedGoogle Scholar
- Broad WJ. White House debate on smallpox slows plan for wide vaccination. New York Times 2002 Oct. 13; 20.
- De BK, Bragg SL, Sanden GN, Wilson KE, Diem LA, Marston CK, A two-component direct fluorescent-antibody assay for rapid identification of Bacillus anthracis. Emerg Infect Dis. 2002;8:1060–5.PubMedGoogle Scholar
- Espy MJ, Cockerill FR III, Meyer RF, Bowen MD, Poland GA, Hadfield TL, Detection of smallpox virus DNA by LightCycler PCR. J Clin Microbiol. 2002;40:1985–8. DOIPubMedGoogle Scholar
- Berdal BP, Mehl R, Haaheim H, Loksa M, Grunow R, Burans J, Field detection of Francisella tularensis. Scand J Infect Dis. 2000;32:287–91. DOIPubMedGoogle Scholar
- Neergard L. Scientists work on smallpox medicines. Associated Press Online, June 2 2002. Available from: URL:http://www.lexis-nexis.com
- Centers for Disease Control and Prevention. Biological diseases/agents: category A. Atlanta (GA): The Centers; 2003. Available from: URL:http://www.bt.cdc.gov/agent/agentlist.asp\#categoryadiseases
- Report on blood collection and transfusion in the United States in 1999. Bethesda (MD): National Blood Data Resource Center; 2000.
- Cox DR. Renewal theory. London: Methuen & Co. Ltd.; 1967.
- Anderson RM, May RM. Infectious diseases of humans: dynamics and control. New York: Oxford University Press; 1991.
- Gani R, Leach S. Transmission potential of smallpox in contemporary populations. Nature. 2001;414:748–51. DOIPubMedGoogle Scholar