Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 10, Number 11—November 2004
Research

Histopathologic Improvement with Lymphedema Management, Léogâne, Haiti

Susan F. Wilson*, Jeannette Guarner*, Alix L. Valme†, Jacky Louis-Charles†, Tara L. Jones*, and David G. Addiss*Comments to Author 
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Hôpital Ste. Croix, Léogâne, Haiti

Main Article

Table 3

Number and percentage of skin biopsy specimens in which histopathologic features were detected in 27 patients practicing lymphedema management, Léogâne, Haitia

Location in skin Histopathologic characteristic 1st biopsy (N = 27) n (%) 2nd biopsy (N = 27) n (%) p value
Epidermis Hyperkeratosis 14 (52) 12 (44) 0.59
Hypergranulosis 5 (18) 1 (4) 0.09
Acanthosis 7 (26) 3 (11) 0.16
Superficial dermis Fibrolamellar hyperplasia 16 (59) 11 (41) 0.18
Condensed collagen 10 (37) 5 (18) 0.13
Perivascular fibrosis 4 (15) 1 (4) 0.17
Perivascular infiltrate
   Acute 0 (0) 0 (0)
   Chronic 27 (100) 16 (59) 0.0002
   Pronounced intensity 10 (37) 3 (11) 0.03
   Presence of plasma cells 7 (26) 4 (15) 0.31
Deep dermis Perivascular fibrosis 14 (52) 6 (22) 0.02
Perivascular infiltrate
   Acute 0 (0) 0 (0)
   Chronic 25 (93) 21 (78) 0.12
   Pronounced intensity 9 (33) 6 (22) 0.37
   Presence of plasma cells 18 (67) 18 (67) 1
Periadnexal infiltrate
   Acute 0 (0) 0 (0)
   Chronic 19 (70) 9 (33) 0.007
   Pronounced intensity 7 (26) 0 (0) 0.005
Subcutaneous tissue Infiltrate in fibrous septa
   Acute 0 (0) 0 (0)
   Chronic 10 (37) 10 (37) 1
   Pronounced intensity 5 (18) 1 (4) 0.09

aFor each patient, the second biopsy specimen was taken near the same site on the same lymphedematous leg ≈1 year after the first biopsy.

Main Article

Page created: April 22, 2011
Page updated: April 22, 2011
Page reviewed: April 22, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external