Volume 10, Number 2—February 2004
THEME ISSUE
2004 SARS Edition
Laboratory Study
Detection of SARS Coronavirus in Patients with Suspected SARS
Kwok H. Chan*, Leo L.L.M. Poon†, V.C.C. Cheng*, Yi Guan†, I.F.N. Hung*, Joseph S.M. Peiris‡
, Loretta Y.C. Yam§, Wing H. Seto*, Kwok Y. Yuen†, and Joseph S. Malik Peiris†
, Loretta Y.C. Yam§, Wing H. Seto*, Kwok Y. Yuen†, and Joseph S. Malik Peiris†
Table 2
Serologic response to SARS coronavirusa
| Clinical category | No. of patients | Paired sera available for study | No (%) of patients with 4-fold rise in antibody titer to SARS-CoV |
|---|---|---|---|
| Clinical SARS | 590 | 417 | 384 (92.1) |
| Suspected SARS | 79 | 11 | 1 (9.1) |
| Not SARS | 379 | 25 | 2 (8.0) |
| Controls | 45 | 45 | 0 (0.0) |
aSARS, severe acute respiratory syndrome; SARS-CoV, severe acute respiratory syndrome coronavirus.
bAn additional 47 convalescent-phase sera were subsequently tested without any further evidence of antibody to SARS-CoV.
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