Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 13, Number 10—October 2007
Dispatch

Chlorine Inactivation of Highly Pathogenic Avian Influenza Virus (H5N1)

Eugene W. Rice*Comments to Author , Noreen J. Adcock*, Mano Sivaganesan*, Justin D. Brown†, David E. Stallknecht†, and David E. Swayne‡
Author affiliations: *US Environmental Protection Agency, Cincinnati, Ohio, USA; †University of Georgia, Athens, Georgia, USA; ‡US Department of Agriculture, Athens, Georgia, USA;

Main Article

Table 2

Inactivation of HPAI (H5N1) virus by free chlorine at 5°C*

Strain pH Time, s Free chlorine, mg/L Virus titer log10 TCID50/mL Log10 reduction
Hong Kong† 7 0 2.08 5.32 NA
15 ND <2.17 >3.15
30 0.65 <2.17 >3.15
60 0.52 <2.17 >3.15
8 0 2.08 5.70 NA
15 ND 3.88 1.82
30 0.76 2.67 3.03
60
 0.59
 <2.17
 >3.53
Mongolia‡ 7 0 1.86 5.26 NA
15 ND <2.17 >3.09
30 0.85 <2.17 >3.09
60 0.77 <2.17 >3.09
8 0 2.04 5.53 NA
15 ND 3.39 2.14
30 1.10 <2.17 >3.36
60 1.08 <2.17 >3.36

*HPAI, highly pathogenic avian influenza; TCID50, median 50% tissue culture infectious dose; NA, not applicable; ND, not determined.
†A/chicken/Hong Kong/D-0947/2006.
‡A/WhooperSwan/Mongolia/244/2005.

Main Article

Page created: July 06, 2010
Page updated: July 06, 2010
Page reviewed: July 06, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external