Volume 13, Number 2—February 2007
Synopsis
Immune Cell Apoptosis Prevention as Potential Therapy for Severe Infections
Figure 3
![Decreased apoptosis caused by overexpression of Bcl-2 protein in a mouse model of plague. Wild-type mice (A) and mice that overexpressed Bcl-2 in lymphocytes (B) were injected intranasally with Yersinia pestis. Thymuses were obtained at 72 h postinfection and stained by using the terminal deoxynucleotidyl method as a marker of apoptotic cell death. Note the decrease in apoptotic cells in the thymus of the Bcl-2 transgenic mouse (magnification ×400).](/eid/images/06-0963-F3.jpg)
Figure 3. Decreased apoptosis caused by overexpression of Bcl-2 protein in a mouse model of plague. Wild-type mice (A) and mice that overexpressed Bcl-2 in lymphocytes (B) were injected intranasally with Yersinia pestis. Thymuses were obtained at 72 h postinfection and stained by using the terminal deoxynucleotidyl method as a marker of apoptotic cell death. Note the decrease in apoptotic cells in the thymus of the Bcl-2 transgenic mouse (magnification ×400).
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