Volume 13, Number 2—February 2007
Research
Meningococcal Disease in South Africa, 1999–2002
, Mignon du Plessis*, Anthony M. Smith*, Linda de Gouveia*, Keith P. Klugman*†, Anne von Gottberg* , and for the Group for EntericRespiratoryGERMS-SA
Table 1
Provincial distribution of reported invasive meningococcal disease by serogroup and date of study, South Africa
| Year | Serogroup | Province* | Total | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| EC | FS | GA | KZ | LIM | MP | NC | NW | WC | N (%)† | ||
| Aug 1999–Jul 2000 | A | –‡ | – | 9 | 1 | – | – | – | 1 | 4 | 15 (8) |
| B | 6 | – | 12 | 4 | – | 3 | – | – | 81 | 106 (56) | |
| C | 2 | 2 | 2 | – | – | – | – | – | 14 | 20 (10) | |
| W135 | – | – | 3 | 3 | – | – | – | – | 4 | 10 (5) | |
| X | – | – | 1 | – | – | – | – | – | 2 | 3 (2) | |
| Y | 2 | 6 | 10 | 7 | – | – | – | – | 11 | 36 (19) | |
| No isolate available | 2 | 9 | 10 | 4 | 2 | 2 | 10 | 39 | |||
| Total | 12 | 8 | 46 | 25 | 4 | 5 | – | 3 | 126 | 229 | |
| Aug 2000–Jul 2001 | A | – | – | 34 | 2 | – | 5 | – | 3 | – | 44 (23) |
| B | 6 | 3 | 13 | 3 | – | 1 | – | 1 | 56 | 83 (43) | |
| C | 3 | – | 3 | – | – | 1 | – | 1 | 4 | 12 (6) | |
| W135 | – | – | 7 | – | – | – | – | – | 1 | 8 (4) | |
| X | – | – | 1 | – | – | – | – | – | 1 | 2 (1) | |
| Y | 2 | 14 | 13 | 1 | 2 | 3 | 1 | 1 | 5 | 42 (22) | |
| Z | – | – | 2 | – | – | – | – | – | – | 2 (1) | |
| No isolate available | 3 | 51 | 2 | 6 | 1 | 19 | 82 | ||||
| Total | 14 | 17 | 124 | 8 | 8 | 11 | 1 | 6 | 86 | 275 | |
| Aug 2001–Jul 2002 | A | – | – | 78 | 1 | – | 1 | – | 2 | 1 | 83 (36) |
| B | 3 | 4 | 15 | – | – | – | 1 | 1 | 38 | 62 (27) | |
| C | 1 | – | 6 | – | – | – | 1 | – | 10 | 18 (8) | |
| 29E | – | – | – | – | – | – | – | – | 1 | 1 (<1) | |
| W135 | 1 | – | 9 | – | – | – | – | 1 | 2 | 13 (6) | |
| X | – | – | 2 | – | – | – | – | – | 1 | 3 (1) | |
| Y | 3 | 14 | 20 | 4 | – | 1 | 2 | 1 | 7 | 52 (22) | |
| No isolate available | 3 | 2 | 51 | 5 | 10 | 1 | 1 | 45 | 118 | ||
| Total | 11 | 20 | 181 | 10 | – | 12 | 5 | 6 | 105 | 350 | |
*EC, Eastern Cape; FS, Free State; GA, Gauteng; KZ, KwaZulu Natal; LIM, Limpopo; MP, Mpumalanga; NC, Northern Cape; NW, North West; WC, Western Cape.
†Percentages denote the percentage of that particular serogroup over the total number of serogrouped isolates for that year.
‡No cases reported.
1GERMS-SA: Sandeep Vasaikar (Eastern Cape); Nolan Janse van Rensberg, Peter Smith (Free State); Khatija Ahmed, Heather Crewe-Brown, Mike Dove, Charles Feldman, Alan Karstaedt, Olga Perovic, Pyu-Pyu Sein, Ruth Lekalakala (Gauteng); Wim Sturm (KwaZulu Natal); Ken Hamese (Limpopo); Keith Bauer (Mpumalanga); Denise Roditi, Rena Hoffmann, Lynne Liebowitz, John Simpson, Andrew Whitelaw (Western Cape); Adrian Brink (AMPATH); Claire Heney (Lancet); Martinus Senekal (PathCare).