Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 13, Number 9—September 2007
Dispatch

Mokola Virus in Domestic Mammals, South Africa

Claude T. Sabeta*†Comments to Author , Wanda Markotter†, Debrah K. Mohale*, Wonderful Shumba*, Alexander I. Wandeler‡, and Louis H. Nel†
Author affiliations: *Agricultural Research Council–Onderstepoort Veterinary Institute, Pretoria, South Africa; †University of Pretoria, Pretoria, South Africa; ‡Canadian Food Inspection Agency, Nepean, Ontario, Canada;

Main Article

Figure

Phylogenetic tree based on 267 nt of partial nucleoprotein gene sequences of Moloka virus (MOKV) identified with the N1-N2 primer set as described (12). The tree shows phylogenetic positions of 2 recently identified cases of MOKV infection from South Africa (MOKV173/06 from a cat and MOKV404/05 from a dog) (in boldface) relative to previously characterized MOKV isolates from South Africa (SA) and Zimbabwe (ZIM) and Lagos bat virus (LBV) as the outgroup. GenBank accession nos. are shown in parenthesis. Bootstrap support values >70% are considered significant and indicated. Scale bar shows nucleotide substitutions per site.

Figure. Phylogenetic tree based on 267 nt of partial nucleoprotein gene sequences of Moloka virus (MOKV) identified with the N1-N2 primer set as described (12). The tree shows phylogenetic positions of 2 recently identified cases of MOKV infection from South Africa (MOKV173/06 from a cat and MOKV404/05 from a dog) (in boldface) relative to previously characterized MOKV isolates from South Africa (SA) and Zimbabwe (ZIM) and Lagos bat virus (LBV) as the outgroup. GenBank accession nos. are shown in parenthesis. Bootstrap support values >70% are considered significant and indicated. Scale bar shows nucleotide substitutions per site.

Main Article

References
  1. Fauquet  CM, Mayo  MA, Maniloff  J, Desselberger  U, Ball  LA. Virus taxonomy: the classification and nomenclature of viruses. The eighth report of the international committee on taxonomy of viruses. San Diego: Academic Press; 2004. p. 623–31.
  2. Shope  RE, Murphy  FA, Harrison  AK, Causey  OR, Kemp  GE, Simpson  DI, Two African viruses serologically and morphologically related to rabies virus. J Virol. 1970;6:690–2.PubMedGoogle Scholar
  3. Kemp  GE, Causey  OR, Moore  DL, Odelola  A, Fabiyi  A. Mokola virus. Further studies on IbAn 27377, a new rabies-related etiologic agent of zoonosis in Nigeria. Am J Trop Med Hyg. 1972;21:356–9.PubMedGoogle Scholar
  4. Familusi  JB, Osunkoya  BO, Moore  DL, Kemp  GE, Fabiyi  A, Moore  DL. A fatal human infection with Mokola virus. Am J Trop Med Hyg. 1972;21:959–63.PubMedGoogle Scholar
  5. Le Gonidec  G, Rickenbach  A, Robin  Y, Heme  G. Isolation of a strain of Mokola virus in Cameroon. Ann Microbiol (Paris). 1978;129:245–9.PubMedGoogle Scholar
  6. Saluzzo  JF, Rollin  PE, Daugard  C, Digoutte  JP, Georges  AJ, Sureau  P. Premier isolement du virus Mokola a partir d’une rongeur (Lophuromys sikapusi). Ann Inst Pasteur Virol. 1984;135E:57–66. DOIGoogle Scholar
  7. Foggin  CM. Rabies and rabies-related viruses in Zimbabwe: historical, virological and ecological aspects [doctoral dissertation]. Harare (Zimbabwe): University of Zimbabwe; 1988.
  8. Mebatsion  T, Cox  JH, Frost  JW. Isolation and characterisation of 115 street rabies virus isolates from Ethiopia by using monoclonal antibodies: identification of 2 isolates of Mokola and Lagos bat viruses. J Infect Dis. 1992;166:972–7.PubMedGoogle Scholar
  9. Meredith  CD, Nel  LH, von Teichman  BF. A further isolation of Mokola virus in South Africa. Vet Rec. 1996;138:119–20.PubMedGoogle Scholar
  10. von Teichman  BF, de Koker  WC, Bosch  SJ, Bishop  GC, Meredith  CD, Bingham  J. Mokola virus infection: description of recent South African cases and a review of the virus epidemiology. J S Afr Vet Assoc. 1998;69:169–71.PubMedGoogle Scholar
  11. Bingham  J, Javangwe  S, Sabeta  CT, Wandeler  AI, Nel  LH. Report of isolations of unusual lyssaviruses (rabies and Mokola virus) identified retrospectively from Zimbabwe. J S Afr Vet Assoc. 2001;72:92–4.PubMedGoogle Scholar
  12. Nel  L, Jacobs  J, Jaftha  J, von Teichman  B, Bingham  J. New cases of Mokola virus infection in South Africa: a genotypic comparison of Southern African virus isolates. Virus Genes. 2000;20:103–6. DOIPubMedGoogle Scholar
  13. Paweska  JT, Blumberg  LH, Liebenberg  C, Hewlett  RH, Grobelaar  AA, Leman  PA, Fatal human infection with rabies-related Duvenhage virus, South Africa. Emerg Infect Dis. 2006;12:1965–7.PubMedGoogle Scholar
  14. Markotter  W, Randles  J, Rupprecht  CE, Sabeta  CT, Taylor  PJ, Wandeler  AI, Lagos bat virus, South Africa. Emerg Infect Dis. 2006;12:504–6.PubMedGoogle Scholar
  15. Markotter  W, Kuzmin  I, Rupprecht  CE, Randles  J, Sabeta  CT, Wandeler  AI, Isolation of Lagos bat virus from water mongoose. Emerg Infect Dis. 2006;12:1913–8.PubMedGoogle Scholar

Main Article

Page created: July 01, 2010
Page updated: July 01, 2010
Page reviewed: July 01, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external