Volume 14, Number 2—February 2008
Research
Streptococcus pneumoniae Serotype 19A in Children, South Korea
Eun Hwa Choi*†, So Hee Kim*, Byung Wook Eun*, Sun Jung Kim†, Nam Hee Kim‡, Hoan Jong Lee*¶
, and Jina Lee§
, and Jina Lee§
Table 2
Antimicrobial susceptibility and mef and erm prevalence of serogroup 19 pneumococcal isolates from children in South Korea, 1991–2006, according to sequence type
| CC or ST* (no. strains) | Serotypes | Multidrug resistance† | MIC50 (range) in µg/mL for each antimicrobial drug |
mef/erm determinants | ||
|---|---|---|---|---|---|---|
| Penicillin | Cefotaxime | Erythromycin | ||||
| CC271-related‡ (116) | 19A, 19F | Yes | 1.5 (1.0–3.0) | 1.0 (0.75–4.0) | >256 (>256) | mef+, erm+ |
| ST1203 (1) | 19F | No | 0.5 | 0.25 | 0.5 | mef |
| ST1374 (4) | 19A | Yes | 0.06 (0.04–0.06) | 0.12 (0.09–0.12) | >256 (>256) | mef |
| ST2394 (1) | 19A | Yes | 1.0 | 0.5 | 2.0 | mef+, erm |
| ST2395 (3) | 19F | Yes | 4.0 (4.0) | 2.0 (1.0–2.0) | 2.0 (2.0) | mef+, erm |
| ST2399 (1) | 19F | Yes | 0.12 | 0.25 | 8.0 | mef+, erm |
*CC, clonal complex; ST, sequence type.
†Resistant to at least 3 antimicrobial drug classes.
‡CC271-related sequence types: ST320 (59 isolates), ST271 (14), ST236 (14), ST283 (7), ST1451 (1), ST1464 (10), ST2395 (3), ST2695 (3), and 1 isolate of each of ST1412, ST1417, ST2396, ST2397, ST2398, ST2694, ST2696, ST2697, and ST2698.
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