Volume 15, Number 12—December 2009
Dispatch
Transplacental Transmission of Bluetongue Virus 8 in Cattle, UK
Karin E. Darpel
, Carrie A. Batten, Eva Veronesi, Susanna Williamson, Peter Anderson, Mike Dennison, Stuart Clifford, Ciaran Smith, Lucy Philips, Cornelia Bidewell, Katarzyna Bachanek-Bankowska, Anna Sanders, Abid Bin-Tarif, Anthony J. Wilson, Simon Gubbins, Peter P.C. Mertens, Chris A. Oura, and Philip S. Mellor
, Carrie A. Batten, Eva Veronesi, Susanna Williamson, Peter Anderson, Mike Dennison, Stuart Clifford, Ciaran Smith, Lucy Philips, Cornelia Bidewell, Katarzyna Bachanek-Bankowska, Anna Sanders, Abid Bin-Tarif, Anthony J. Wilson, Simon Gubbins, Peter P.C. Mertens, Chris A. Oura, and Philip S. Mellor
Table
Bluetongue virus real-time reverse transcription–PCR results from follow-up sampling of calves with initial positive results, United Kingdom, December 20, 2007, to March 15, 2008*
| Calf no. | First BTV result, age, d (Ct) | Retest results, age, d (Ct) |
Age, d, when PCR negative | Estimated gestation, d† | ||||
|---|---|---|---|---|---|---|---|---|
| Retest 1 | Retest 2 | Retest 3 | Retest 4 | Retest 5 | ||||
| 1 | 15 (25) | 28 (26) | 44 (26) | 58 (28.5) | 72 (32.5) | 91 (neg) | 91 | 82–219 |
| 3 | 38 (31) | 47 (32) | 61 (35.5) | 81 (neg) | NT | NT | 81 | 106–243 |
| 10 | 79 (32) | 106 (33.5) | 120 (34) | 137 (neg) | 158 (neg) | NT | 137 | 140–197 |
| 12 | 81 (28) | 108 (30) | 122 (31) | 139 (34) | 160 (neg) | NT | 160 | 142–199 |
| 13 | 4 (33) | 31 (36.5) | 45 (neg) | 62 (neg) | 83 (neg) | NT | 45 | 65–122 |
| 14 | 28 (26) | 48 (29) | 55 (32) | 69 (neg) | 86 (neg) | 107 (neg) | 69 | 154–209 |
| 15 | 70 (32) | 97 (neg) | 111 (neg) | 128 neg) | 149 (neg) | NT | 97 | 196–251 |
| 20 | 17 (31) | 44 (32.5) | 58 (33.5) | 75 (neg) | 96 (neg | NT | 75 | 78–128 |
| 25 | 27 (29.5) | 41 (29) | 55 (30.5) | 69 (36) | NT | NT | >69‡ | 145–202 |
| 28 | 1 (23) | 26 (25) | 35 (26) | NT | NT | >35‡ | 101–181 | |
| 29 | 1 (27) | 12 (27.5) | Calf died | 45–182 | ||||
| 41 | 47 (28) | 61 (29.5) | NT | NT | NT | NT | >61‡ | 79–126 |
| 45 | 22 (27) | 40 (30.5) | 61 (34) | NT | NT | NT | >61‡ | 52–130 |
| 47 | 25 (26.5) | 39 (29) | 66 (38) | NT | NT | NT | >66‡ | 52–189 |
| 49 (twin with 50) | 46 (29) | 60 (36) | 87 (neg) | NT | NT | NT | 87 | 73–136 |
| 50 (twin with 49) | 46 (29) | 60 (36.5) | 87 (neg) | NT | NT | NT | 87 | 73–136 |
| 55 | 21 (25.5) | 48 (31.5) | NT | NT | NT | >48‡ | 34–172 | |
*BTV, bluetongue virus; Ct, cycle threshold; neg, negative; NT, not tested.
†Estimated stage of gestation at which transplacental infection may have occurred
‡These calves could not be followed up for farm management reasons or because the project had ended.
Page created: December 09, 2010
Page updated: December 09, 2010
Page reviewed: December 09, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.