Volume 15, Number 5—May 2009
Dispatch
Probable Congenital Babesiosis in Infant, New Jersey, USA
Table 2
Clinical data | Reference case 1 | Reference case 2 | Present case |
---|---|---|---|
Infant’s age at time of illness | 30 d | 5 wk | 26 d |
Time of maternal tick bite before delivery |
1 wk |
7 wk |
4 wk |
Serologic test results for Babesia spp. | |||
Mother | Pos | Pos | Pos |
Infant |
Pos |
Pos |
Pos |
Clinical findings | Fever, irritability, pallor, hepatosplenomegaly | Lethargy, poor feeding, pallor | Fever, poor feeding, irritability, pallor, scleral icterus, hepatosplenomegaly |
Parasitemia, % | 5 | 4.4 | 15 |
Treatment (duration) | Ampicillin and gentamicin (3 d); clindamycin and quinine sulfate (10 d) | Clindamycin and quinine sulfate (12 d); azithromycin (10 d) | Ceftriaxone (8 d); atovaquone and azithromycin (10 d) |
*All infants’ history of tick exposure was negative, and all recovered.
References
- Cunha BA, Barnett B. Babesiosis. eMedicine Journal [serial online]. 2006 Aug [cited 2007 May 14]. Available from http://www.emedicine.com/med/topic195.htm
- Homer MJ, Aguilar-Delfin I, Telford SR III, Krause PJ, Persing DH. Babesiosis. Clin Microbiol Rev. 2000;13:451–69. DOIPubMedGoogle Scholar
- Esernio-Jenssen D, Scimeca PG, Benach JL, Tenenbaum MJ. Transplacental/perinatal babesiosis. J Pediatr. 1987;110:570–2. DOIPubMedGoogle Scholar
- New DL, Quinn JB, Qureshi MZ, Sigler SJ. Vertically transmitted babesiosis. J Pediatr. 1997;131:163–4. DOIPubMedGoogle Scholar
- Fox LM, Wingerter S, Ahmed A, Arnold A, Chou J, Rhein L, Neonatal babesiosis: case report and review of the literature. Pediatr Infect Dis J. 2006;25:169–73. DOIPubMedGoogle Scholar
- Scimeca PG, Weinblatt ME, Schonfeld G, Kaplan MH, Kochen JH. Babesiosis in two infants from Eastern Long Island, NY. Am J Dis Child. 1986;140:971.PubMedGoogle Scholar
- Wittner M, Rowin KS, Tanowitz HB, Hobbs JF, Saltzman S, Wenz B, Successful chemotherapy of transfusion babesiosis. Ann Intern Med. 1982;96:601–4.PubMedGoogle Scholar
- Dobroszycki J, Herwaldt BL, Boctor F, Miller JR, Linden J, Eberhard ML, A cluster of transfusion-associated babesiosis cases traced to a single asymptomatic donor. JAMA. 1999;281:927–30. DOIPubMedGoogle Scholar
- Kjemtrup AM, Lee B, Fritz CL, Evans C, Chervenak M, Conrad PA. Investigation of transfusion transmission of a WA1-type babesial parasite to a premature infant in California. Transfusion. 2002;42:1482–7. DOIPubMedGoogle Scholar
- Raju M, Salazar JC, Leopold H, Krause PJ. Atovaquone and azithromycin treatment for babesiosis in an infant. Pediatr Infect Dis J. 2007;26:181–3. DOIPubMedGoogle Scholar
- Krause PJ, Lepore T, Sikand VK, Gadbaw J Jr, Burke G, Telford SR III, Atovaquone and azithromycin for the treatment of babesiosis. N Engl J Med. 2000;343:1454–8. DOIPubMedGoogle Scholar
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