Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 16, Number 11—November 2010
Dispatch

Hepatitis E Virus Infection in Sheltered Homeless Persons, France

Mamadou Kaba, Philippe Brouqui, Hervé Richet, Sekené Badiaga, Pierre Gallian, Didier Raoult, and Philippe ColsonComments to Author 
Author affiliations: Centre Hospitalo–Universitaire Timone, Marseille, France (M. Kaba, P. Colson); Université de la Méditerranée, Marseille (M. Kaba, P. Brouqui, H. Richet, S. Badiaga, D. Raoult, P. Colson); Hôpital Nord, Marseille (P. Brouqui, S. Badiaga); d Etablissement Français du Sang Alpes-Méditerranée, Marseille (P. Gallian)

Main Article

Figure

Phylogenetic tree based on partial nucleotide sequences (275 bp) corresponding to the 5′-end open reading frame 2 region of the hepatitis E virus (HEV) genome. Phylogenetic analysis included HEV sequence recovered in the present study (black circle, boldface and underlined; GenBank accession no. FJ71877) and sequences corresponding to the HEV sequences hits with the highest BLASTn score (http://blast.ncbi.nlm.nih.gov) to this sequence (black triangles), previously recovered in our laboratory (bo

Figure. Phylogenetic tree based on partial nucleotide sequences (275 bp) corresponding to the 5′-end open reading frame 2 region of the hepatitis E virus (HEV) genome. Phylogenetic analysis included HEV sequence recovered in the present study (black circle, boldface and underlined; GenBank accession no. FJ71877) and sequences corresponding to the HEV sequences hits with the highest BLASTn score (http://blast.ncbi.nlm.nih.gov) to this sequence (black triangles), previously recovered in our laboratory (boldface), and of previously determined genotypes and subtypes (2) (in parentheses). Shading indicates sequences previously isolated in our laboratory. Bootstrap values >60% of 1,000 resamplings of the data are indicated. Avian HEV sequence AY043166 was used as an outgroup. The names of HEV sequences are labeled as follows: GenBank accession no., host, and country of origin where recovered. Scale bar indicates number of nucleotide substitutions per site.

Main Article

References
  1. Dalton  HR, Bendall  R, Ijaz  S, Banks  M. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis. 2008;8:698709. DOIPubMedGoogle Scholar
  2. Lu  L, Li  C, Hagedorn  CH. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol. 2006;16:536. DOIPubMedGoogle Scholar
  3. Teo  CG. Hepatitis E indigenous to economically developed countries: to what extent a zoonosis? Curr Opin Infect Dis. 2006;19:4606. DOIPubMedGoogle Scholar
  4. Badiaga  S, Raoult  D, Brouqui  P. Preventing and controlling emerging and reemerging transmissible diseases in the homeless. Emerg Infect Dis. 2008;14:13539. DOIPubMedGoogle Scholar
  5. Leon  P, Venegas  E, Bengoechea  L, Rojas  E, Lopez  JA, Elola  C, Prevalence of infections by hepatitis B, C, D and E viruses in Bolivia. Rev Panam Salud Publica. 1999;5:14451. DOIPubMedGoogle Scholar
  6. Smith  HM, Reporter  R, Rood  MP, Linscott  AJ, Mascola  LM, Hogrefe  W, Prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown Los Angeles. J Infect Dis. 2002;186:16736. DOIPubMedGoogle Scholar
  7. Kaba  M, Davoust  B, Marie  JL, Barthet  M, Henry  M, Tamalet  C, Frequent transmission of hepatitis E virus among piglets in farms in Southern France. J Med Virol. 2009;81:17509. DOIPubMedGoogle Scholar
  8. Boutrouille  A, Bakkali-Kassimi  L, Cruciere  C, Pavio  N. Prevalence of anti-hepatitis E virus antibodies in French blood donors. J Clin Microbiol. 2007;45:200910. DOIPubMedGoogle Scholar
  9. Mansuy  JM, Legrand-Abravanel  F, Calot  JP, Peron  JM, Alric  L, Agudo  S, High prevalence of anti-hepatitis E virus antibodies in blood donors from South West France. J Med Virol. 2008;80:28993. DOIPubMedGoogle Scholar
  10. Bendall  R, Ellis  V, Ijaz  S, Ali  R, Dalton  H. A comparison of two commercially available anti-HEV IgG kits and a re-evaluation of anti-HEV IgG seroprevalence data in developed countries. J Med Virol. 2010;82:799805. DOIPubMedGoogle Scholar
  11. Legrand-Abravanel  F, Thevenet  I, Mansuy  JM, Saune  K, Vischi  F, Peron  JM, Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections. Clin Vaccine Immunol. 2009;16:7724. DOIPubMedGoogle Scholar
  12. Gessoni  G, Manoni  F. Hepatitis E virus infection in north-east Italy: serological study in the open population and groups at risk. J Viral Hepat. 1996;3:197202. DOIPubMedGoogle Scholar
  13. Sylvan  SP. The high rate of antibodies to hepatitis E virus in young, intravenous drug-abusers with acute hepatitis B virus infection in a Swedish community: a study of hepatitis markers in individuals with intravenously or sexually acquired hepatitis B-virus infection. Scand J Infect Dis. 1998;30:42930.PubMedGoogle Scholar
  14. Christensen  PB, Engle  RE, Jacobsen  SE, Krarup  HB, Georgsen  J, Purcell  RH. High prevalence of hepatitis E antibodies among Danish prisoners and drug users. J Med Virol. 2002;66:4955. DOIPubMedGoogle Scholar
  15. Thomas  DL, Yarbough  PO, Vlahov  D, Tsarev  SA, Nelson  KE, Saah  AJ, Seroreactivity to hepatitis E virus in areas where the disease is not endemic. J Clin Microbiol. 1997;35:12447.PubMedGoogle Scholar

Main Article

Page created: March 03, 2011
Page updated: March 03, 2011
Page reviewed: March 03, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external