Volume 16, Number 4—April 2010
CME ACTIVITY - Research
Community-associated Methicillin-Resistant Staphylococcus aureus Strains in Pediatric Intensive Care Unit1
, Karen C. Carroll, Tracy Ross, K. Alexander Shangraw, and Trish M. Perl
Table 2
Characteristics of patients with and without MRSA colonization at the time of PICU admission, The Johns Hopkins University Hospital, Baltimore, MD, USA, March 2007–May 2008*
| Characteristic | Group 1,† n = 72 | Group 2,‡ n = 1,117 | Group 3, n = 24§ | p value | |
|---|---|---|---|---|---|
| Group 2 vs. group 1 | Group 3 vs. group 1 | ||||
| Demographic | |||||
| Median age, y (IQR) | 3 (0–7.5) | 5 (1–12) | 10.5 (3–13) | 0.02 | <0.01 |
| Male sex | 38 (53) | 616 (55) | 13 (54) | 0.69 | 0.91 |
| Race | |||||
| White | 28 (39) | 640 (57) | 10 (42) | Referent¶ | Referent¶ |
| African American | 39 (54) | 352 (32) | 13 (54) | <0.001 | 0.89 |
| Other | 5 (7) | 126 (11) | 1 (4) | 0.86 | 0.62 |
| Clinical | |||||
| Known MRSA carrier# | 18 (25) | 0 (0) | 24 (100) | ||
| Hospitalization in previous 12 mo | 42 (58) | 308 (28) | 14 (58) | <0.001 | 0.41 |
| Outcomes | |||||
| PICU length of stay,** median (IQR) | 3 (1–7) | 2 (1–4) | 2.5 (1–9) | <0.001 | 0.96 |
| Hospital length of stay,** median (IQR) | 8 (3.5–15.5) | 5 (3–10) | 6 (3/5–14.5) | <0.01 | 0.70 |
*MRSA, methicillin-resistant Staphylococcus aureus; PICU, pediatric intensive care unit; IQR, interquartile range. Values reported as no. (%) unless otherwise specified.
†MRSA colonized: patients who had MRSA grow in an admission nasal surveillance culture or in any clinical culture within 3 days of PICU admission.
‡Not MRSA colonized/no institutional history of MRSA colonization.
§Not MRSA colonized/institutional history of MRSA colonization.
¶Obtained from univariate logistic regression analysis.
#Patients with institutional history of MRSA colonization or infection.
**Data were log transformed before regression analysis to account for skewing.
1These data were presented in part at the Annual Scientific Meeting of the Society of Healthcare Epidemiology of America, Orlando, Florida, USA, April 2008.