Volume 16, Number 6—June 2010
Research
Clonal Expansion of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis, Japan
Yoshiro Murase
, Shinji Maeda, Hiroyuki Yamada, Akihiro Ohkado, Kinuyo Chikamatsu, Kazue Mizuno, Seiya Kato, and Satoshi Mitarai
, Shinji Maeda, Hiroyuki Yamada, Akihiro Ohkado, Kinuyo Chikamatsu, Kazue Mizuno, Seiya Kato, and Satoshi Mitarai
Table 2
Distribution of Mycobacterium tuberculosis spoligotype families among 55 persons with MDR/XDR TB, Japan*
| Spoligotype family | No. (%) cases |
||
|---|---|---|---|
| XDR TB, n = 17 | Non-XDR MDR TB, n = 38 | MDR and XDR TB, n = 55 | |
| Beijing† | 8 (47) | 26 (68) | 34 (62) |
| T | 2 (12) | 5 (13) | 7 (13) |
| LAM | 3 (18) | 0 | 3 (5) |
| U | 0 | 1 (3) | 1 (2) |
| EAI | 0 | 1 (3) | 1 (2) |
| X | 0 | 1 (3) | 1 (2) |
| Unclassified‡ | 4 (24) | 4 (11) | 8 (15) |
*MDR, multidrug-resistant; XDR, extensively drug-resistant; TB, tuberculosis; LAM, Latino-American and Mediterranean; EAI, East-African Indian.
†Includes Beijing-like strains.
‡Unclassified according to the SpolDB4.
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