Volume 6, Number 5—October 2000
Dispatch
Antimicrobial-Drug Use and Changes in Resistance in Streptococcus pneumoniae
Daniel J. Diekema
, Angela B. Brueggemann, and Gary V. Doern
, Angela B. Brueggemann, and Gary V. Doern
Table 4
Analysis of covariance model, with change in penicillin resistance at each of the 23 medical centers as the dependent variable
| Source | Type III sums of squares | Parameter estimate (B) | F | p-value |
|---|---|---|---|---|
| Overall model | 990a | 4.8 | 0.02 | |
| Intercept | 56 | 4.5 | 0.5 | 0.47 |
| ß-lactam use | 893 | 8.6 | 8.7 | 0.008 |
| Macrolide use | 553 | -6.7 | 5.4 | 0.031 |
| Error | 2,054 | |||
| Total | 4,616 | |||
| Corrected total | 3,045 |
aR2 = 0.325
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