Volume 8, Number 1—January 2002
Research
Antimicrobial Drug Resistance in Pathogens Causing Nosocomial Infections at a University Hospital in Taiwan, 1981-1999
Po-Ren Hsueh*†, Mei-Ling Chen*†, Chun-Chuan Sun†, Wen-Hwei Chen†, Hui-Ju Pan*†, Li-Seh Yang†, Shan-Chwen Chang*†, Shen-Wu Ho*†, Chin-Yu Lee†, Wei-Chuan Hsieh†, and Kwen-Tay Luh*†
Table 2
Selected antimicrobial resistant pathogens associated with nosocomial infection at National Taiwan University Hospital from 1981 to 1999
| Resistant pathogen | % resistance (all patients/in intensive care unit patients/in patients in general wards) | |||
|---|---|---|---|---|
| 1981-1986 | 1987-1992 | 1993-1998 | 1999 | |
| Methicillin-resistant Staphylococcus aureus | 20.2/27.8/19.5 | 31.4/58.5/26.6 | 64.8/86.9/56.7 | 69.3/87.4/60.2 |
| Methicillin-resistant CoNSa | 72.2/88.2/70.8 | 74.0/83.9/71.5 | 79.0/88.7/75.1 | 90.6/90.9/90.5 |
| Penicillin-resistant enterococci | 5.9/6.8/5.8 | 20.7/30/19.6 | 19.5/22.6/18.7 | 35.9/40.9/27.8 |
| Gentamicin-resistant enterococci | 0.0/0.0/0.0 | 71.0/71.4/70.9 | 61.5/67.2/60.0 | 50.0/39.3/55.2 |
| Cefotaxime-resistant Escherichia coli | 1.6/0.0/1.7 | 2.8/8.6/2.5 | 6.8/13.1/6.2 | 12.3/10.3/12.7 |
| Cefotaxime-resistant Klebsiella pneumoniae | 4.9/8.8/3.9 | 7.4/16.9/5.6 | 22.8/50.5/15.6 | 16.5/40.0/9.3 |
| Cefotaxime-resistant Enterobacter spp. | 35.8/52.4/32.4 | 49.7/55.7/47.7 | 57.6/67.0/53.6 | 50.9/61.8/46.2 |
| Cefotaxime-resistant Pseudomonas aeruginosa | 24.2/20.0/25.0 | 16.1/24.3/12.1 | 10.2/16.9/7.8 | 11.2/17.6/8.1 |
| Imipenem-resistant P. aeruginosa | NA | NA | 8.5/18.2/4.9 | 6.7/4.5/7.7 |
| Ciprofloxacin-resistant P. aeruginosa | NA | NA | 8.7/11.6/5.8 | 14.0/18.2/2.9 |
| Imipenem-resistant Acinetobacter baumannii | NA | NA | 6.7/9.1/4.4 | 12.5/23.3/7.6 |
aCoNS = coagulase-negative staphylococci; NA = not available.
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