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Volume 9, Number 5—May 2003
Research

Human Milk Secretory Antibodies against Attaching and Effacing Escherichia coli Antigens

Marita Noguera-Obenza*, Theresa J. Ochoa*, Henry F. Gomez*, M. Lourdes Guerrero†, Irene Herrera-Insua*, Ardythe L. Morrow‡, Guillermo Ruiz-Palacios†, Larry K. Pickering§, Carlos A. Guzman¶, and Thomas G. Cleary*Comments to Author 
Author affiliations: *University of Texas-Houston Medical School, Houston, Texas, USA; †Instituto Nacional de la Nutricion “Salvador Zubiran,” México City, México, D. F.; ‡Cincinnati Children’s Hospital, Cincinnati, Ohio, USA; §Center for Disease Control and Prevention, Atlanta, Georgia, USA; ¶GBF-German National Research Centre for Biotechnology, Braunschweig, Germany

Main Article

Table 3

Comparison of quantity of anti-enterohemorrhagic Escherichia coli secretory immunoglobulin A in milk samples collected from women from Mexico and the United States [median and (range) optical density490]a

          Antigen           Mexico (N=73)           United States (N=50)           p value
          O26
           0.143 (0.016–0.305)
           0.203 (0.030–0.349)
           <0.002
          O55
           0.096 (0–0.411)
           0.057 (0–0.340)
           <0.006
          O111
           0.126 (0–0.390)
           0.143 (0–0.413)
           NS
          O127
           0.124 (0–0.416)
           0.072 (0–0.350)
           <0.004
          O128
           0.026 (0–0.228)
           0.079 (0.003–0.293)
           <0.0000
          O157
           0.061 (0–0.470)
           0.050 (0–0.260)
           NS
          Stx
           0.027 (0–0.470)
           0.043 (0–0.279)
           <0.007
          EspA
           0.283 (0.063–0.666)
           0.201 (0.015–0.490)
           <0.005
          EspB           0.071 (0–0.546)           0.021 (0–0.430)           <0.002

aMann-Whitney test for differences in amounts of antibodies for the two populations; all samples tested at 1:20 dilution; NS, not significant.

Main Article

Page created: December 08, 2010
Page updated: December 08, 2010
Page reviewed: December 08, 2010
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