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Volume 10, Number 2—February 2004
THEME ISSUE
2004 SARS Edition
Laboratory Studies

Serologic and Molecular Biologic Methods for SARS-associated Coronavirus Infection, Taiwan

Ho-Sheng Wu*, Shu-Chun Chiu*, Tsan-Chang Tseng*, Szu-Fong Lin*, Jih-Hui Lin*, Yu-Fen Hsu*, Mei-Ching Wang*, Tsuey-Li Lin*, Wen-Zieh Yang*, Tian-Lin Ferng*, Kai-Hung Huang*, Li-Ching Hsu*, Li-Li Lee*, Jyh-Yuan Yang*, Hour-Young Chen*, Shun-Pi Su*, Shih-Yan Yang*, Ting-Hsiang Lin*, and Ih-Jen Su*Comments to Author 
Author affiliations: *Center for Disease Control, Department of Health, Taiwan, Republic of China

Main Article

Table 2

Specificity, sensitivity, positive and negative predictive values of the tests evaluated for the serodiagnosis of SARS, in comparison to the neutralization testa,b


Neutralization test
Performances of methods evaluated
Method Results Number Positive Negative Sensitivity PPV Specificity NPV









ELISA
Positive
223
220
3
98.2%
98.7%
98.7%
98.4%
Negative
246
4
242
IFA
Positive
252
222
30
99.1%
88.1%
87.8%
99.1%
Negative
217
2
215
ICTc Positive
46
44
2
33.6% 95.7% 98.2% 56.1%
Negative 198 87 111

Main Article

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Page updated: January 26, 2011
Page reviewed: January 26, 2011
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