Volume 10, Number 2—February 2004
THEME ISSUE
2004 SARS Edition
Laboratory Study
Serologic and Molecular Biologic Methods for SARS-associated Coronavirus Infection, Taiwan
Ho-Sheng Wu*, Shu-Chun Chiu*, Tsan-Chang Tseng*, Szu-Fong Lin*, Jih-Hui Lin*, Yu-Fen Hsu*, Mei-Ching Wang*, Tsuey-Li Lin*, Wen-Zieh Yang*, Tian-Lin Ferng*, Kai-Hung Huang*, Li-Ching Hsu*, Li-Li Lee*, Jyh-Yuan Yang*, Hour-Young Chen*, Shun-Pi Su*, Shih-Yan Yang*, Ting-Hsiang Lin*, and Ih-Jen Su*
Table 3
Specificity of the tests evaluated for the serodiagnosis of SARS, in comparison to the neutralization test with regards to samples which tested positive for other diseasesa,b
| Neutralization test |
ELISA |
IFA |
ICT |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pathogen | Parameter | Number | Positive | Negative | Positive | Specificity | Positive | Specificity | Positive | Specificity |
| Hepatitis B virus |
HBs IgM |
3 |
0 |
3 |
0 |
100% |
0 |
100% |
0 |
100% |
| Hepatitis C virus |
IgM |
3 |
0 |
3 |
0 |
100% |
0 |
100% |
0 |
100% |
| Adenovirus |
Total Ab |
1 |
0 |
1 |
0 |
100% |
0 |
100% |
0 |
100% |
| Influenza A virus |
Total Ab |
3 |
0 |
3 |
0 |
100% |
0 |
100% |
0 |
100% |
| Influenza B virus |
Total Ab |
1 |
0 |
1 |
0 |
100% |
0 |
100% |
0 |
100% |
| Dengue virus |
IgM |
2 |
0 |
2 |
0 |
100% |
0 |
100% |
0 |
100% |
| JEV |
IgM |
1 |
0 |
1 |
0 |
100% |
0 |
100% |
0 |
100% |
| Hantavirus |
Total Ab |
1 |
0 |
1 |
0 |
100% |
0 |
100% |
0 |
100% |
| Chlamydia pneumoniae |
IgM |
4 |
0 |
4 |
0 |
100% |
0 |
100% |
0 |
100% |
| Mycoplasma pneumoniae |
IgM |
4 |
0 |
4 |
0 |
100% |
0 |
100% |
0 |
100% |
| Streptococcus pneumoniae |
Total Ab |
1 |
0 |
1 |
0 |
100% |
0 |
100% |
0 |
100% |
| Total non-SARS pathogens | 24 | 0 | 24 | 0 | 100% | 0 | 100% | 0 | 100% | |
Page created: January 26, 2011
Page updated: January 26, 2011
Page reviewed: January 26, 2011
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