Volume 10, Number 5—May 2004
Research
Multidrug-resistant Tuberculosis in Central Asia
Helen Suzanne Cox*
, Juan Daniel Orozco*, Roy Male*, Sabine Ruesch-Gerdes†, Dennis Falzon*, Ian Small*, Darebay Doshetov‡, Yared Kebede§, and Mohammed Aziz¶
, Juan Daniel Orozco*, Roy Male*, Sabine Ruesch-Gerdes†, Dennis Falzon*, Ian Small*, Darebay Doshetov‡, Yared Kebede§, and Mohammed Aziz¶
Table 2
First-line anti-tuberculosis drug resistance results, Karakalpakstan, Uzbekistana
| No. new cases (%) | No. retreatment cases (%) | Total no. (%) | |
|---|---|---|---|
| Total tested | 106 | 107 | 213 |
| Any resistance | 51 (48.1) | 86 (80.4) | 137 (64.3) |
| Monoresistance | |||
| H only | 3 (2.8) | 7 (6.5) | 10 (4.7) |
| R only | 0 | 0 | 0 |
| E only | 0 | 0 | 0 |
| S only | 12 (11.3) | 11 (10.3) | 23 (10.8) |
| Z only | 0 | 1 (0.9) | 1 (0.5) |
| H and R resistance | |||
| MDR | 14 (13.2) | 43 (40.2) | 57 (26.8) |
| HR only | 0 | 1 (0.9) | 1 (0.5) |
| HRE only | 0 | 0 | 0 |
| HRS only | 4 (3.8) | 10 (9.3) | 14 (6.6) |
| HRZ only | 0 | 0 | 0 |
| HRES only | 6 (5.7) | 19 (17.8) | 25 (11.7) |
| HREZ only | 0 | 0 | 0 |
| HRSZ only | 1 (0.9) | 0 | 1 (0.5) |
| HRESZ | 3 (2.8) | 13 (12.1) | 16 (7.5) |
| H + other resistance | |||
| HE only | 0 | 0 | 0 |
| HS only | 13 (12.3) | 15 (14.0) | 28 (13.1) |
| HZ only | 1 (0.9) | 1 | 2 (0.9) |
| HES only | 2 (1.9) | 4 (3.7) | 6 (2.8) |
| HEZ only | 0 | 0 | 0 |
| HSZ only | 1 (.9) | 3 (2.8) | 4 (1.9) |
| HESZ only | 5 (4.7) | 1 (0.9) | 6 (2.8) |
| R + other resistance | |||
| RE only | 0 | 0 | 0 |
| RS only | 0 | 0 | 0 |
| RZ only | 0 | 0 | 0 |
| RES only | 0 | 0 | 0 |
| RESZ only | 0 | 0 | 0 |
| Any drug resistance | |||
| Any H resistance | 39 (36.8) | 74 (69.2) | 113 (53.1) |
| Any R resistance | 14 (13.2) | 43 (40.2) | 57 (26.8) |
| Any E resistance | 16 (15.1) | 37 (34.6) | 53 (24.9) |
| Any S resistance | 47 (44.3) | 76 (71.0) | 123 (57.7) |
| Any Z resistance | 11 (10.4) | 19 (17.8) | 30 (14.1) |
aH, isoniazid; R, rifampin; E, ethambutol; S, streptomycin; Z, pyrizinamide.
Page created: February 22, 2011
Page updated: February 22, 2011
Page reviewed: February 22, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.