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Volume 10, Number 8—August 2004

Serotype III Streptococcus agalactiae from Bovine Milk and Human Neonatal Infections1

John F. Bohnsack*Comments to Author , April A. Whiting*, Gabriela Martinez†, Nicola Jones‡, Elisabeth E. Adderson§, Shauna Detrick*, Anne J. Blaschke-Bonkowsky*, Naiel Bisharat‡, and Marcelo Gottschalk†
Author affiliations: *University of Utah Health Sciences Center, Salt Lake City, Utah, USA; †Faculté de Médicine Vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada; ‡John Radcliffe Hospital, Oxford, United Kingdom; §St. Jude Children’s Research Hospital, Memphis, Tennessee, USA

Main Article

Table 7

Similarities and differences between the two major bovine lineages and related human lineages

Bovine lineage Human lineage Similarities Differences
Same infB allele (A)
No inserted sequences in AW-10, hylb or scpb-lmb sites
Sequence types (STs) the same or differ by <1 allele by multilocus sequence typing (MLST)
Many bovine III-1 strains lack scpb-lmb
H allele III-3 GBSi1 inserted in AW-10 site
No inserted sequence in hylb
STs differ by only two alleles by MLST
III-3 specific sequence tags in genome Different infB allele (H vs C)
BSi1 not found in scpb-lmb
Additional inserted sequences or none in AW-10 site with GBSi1
Some bovine H allele strains lack scp-lmb

Main Article

1Presented in part at the XVth Lancefield International Symposium on Streptococci and Streptococcal Diseases, October 6–11, 2002, Goa, India.

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