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Volume 11, Number 11—November 2005


Neutralizing Antibody Response and SARS Severity

Mei-Shang Ho*, Wei-Ju Chen*, Hour-Young Chen†, Szu-Fong Lin†, Min-Chin Wang†, Jiali Di†, Yen-Ta Lu‡, Ching-Lung Liu‡, Shan-Chwen Chang§, Chung-Liang Chao¶, Chwan-Chuen King§, Jeng-Min Chiou*, Ih-Jen Su#, and Jyh-Yuan Yang†Comments to Author 
Author affiliations: *Academia Sinica, Taipei, Taiwan; †Center for Disease Control, Taipei, Taiwan; ‡Taipei Mackay Memorial Hospital, Taipei, Taiwan; §National Taiwan University, Taipei, Taiwan; ¶Taipei Hospital, Taipei, Taiwan; #National Health Research Institutes, Taipei, Taiwan

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Table 3

Laboratory confirmation of the reported 347 SARS-CoV–infected patients by neutralizing antibody (NT) or by RT-PCR*

NT†/RT-PCR No. (%)
Positive/positive 121 (34.6)
Positive/negative or ND‡ 126 (36.7)
Negative/positive 32 (9.2)
ND‡/positive 68 (19.7)

*SARS-CoV, severe acute respiratory syndrome–associated coronavirus; RT-PCR, reverse transcription–polymerase chain reaction; ND, data not available.
†Positive = NT titer of >1:16 dilution; negative = NT titer <1:16 dilution.
‡Data not available because of loss to follow-up or insufficient number of specimens (n = 8), death (n = 55), or serum collected on the 3rd week (n = 5) of fever onset.

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