Volume 11, Number 5—May 2005
Letter
Toscana Virus and Acute Meningitis, France
Christophe N. Peyrefitte*
, Ivan Devetakov†, Boris Pastorino*, Laurent Villeneuve†, Mael Bessaud*, Philippe Stolidi†, Jerome Depaquit‡, Laurence Segura†, Patrick Gravier*, Fabienne Tock*, Francoise Durand†, Jean-Paul Vagneur†, Hugues J. Tolou*, and Marc Grandadam*
, Ivan Devetakov†, Boris Pastorino*, Laurent Villeneuve†, Mael Bessaud*, Philippe Stolidi†, Jerome Depaquit‡, Laurence Segura†, Patrick Gravier*, Fabienne Tock*, Francoise Durand†, Jean-Paul Vagneur†, Hugues J. Tolou*, and Marc Grandadam*
Table
Arbovirus antibody investigation of samples*
| Viral antigens | CSF† |
Serum 1† |
Serum 2‡ |
|||
|---|---|---|---|---|---|---|
| IgM§ | IgG¶ | IgM | IgG | IgM | IgG | |
| Dengue | 1.16 | 1.08 | 1.06 | 1.06 | 1.32 | 0.94 |
| West Nile | 1.06 | 0.92 | 0.96 | 1.03 | 1.27 | 1.29 |
| Toscana | 2.84 | 0.97 | 2.50 | 0.94 | 48.72 | 3.48 |
| Sandfly fever Sicilian | 0.98 | 0.96 | 0.96 | 0.96 | 1.20 | 0.86 |
| Tickborne encephalitis (Langat) | 0.88 | 1.15 | 1.09 | 0.96 | 1.22 | 0.74 |
| Tahyna | 0.98 | 0.94 | 0.96 | 1.00 | 1.20 | 1.17 |
*CSF, cerebrospinal fluid; Ig, immunoglobulin; MAC-ELISA, immunoglobulin M antigen capture enzyme-linked immunosorbent assay. Values are the ratio OD(viral antigen)/OD(control antigen). Samples were considered positive if the ratio is over 3. Bold values indicate positive results.
†CSF and serum obtained at the onset of the disease.
‡Serum obtained 30 days after the onset of the disease. §MAC-ELISA.
¶Sandwich-ELISA.
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