Volume 11, Number 8—August 2005
Research
Pseudomonas aeruginosa, Staphylococcus aureus, and Fluoroquinolone Use
Table 2
Associations between fluoroquinolone use and resistance in individual years*
FQ use | FQ-R P. aeruginosa |
MRSA |
|||||
---|---|---|---|---|---|---|---|
Total FQ | Levofloxacin | Ciprofloxacin | Total FQ | Levofloxacin | Ciprofloxacin | ||
1999 | R2 | 0.525 | 0.593 | 0.233 | 0.392 | 0.644 | 0.255 |
p | 0.008 | 12 | 0.116 | 0.029 | 0.0017 | 0.0937 | |
n | 12 | 0.003 | 12 | 12 | 12 | 12 | |
2000 | R2 | 0.397 | 0.285 | 0.519 | 0.617 | 0.617 | 0.112 |
p | 0.004 | 0.019 | 0.348 | 0.0001 | 0.0001 | 0.175 | |
n | 19 | 19 | 19 | 18 | 18 | 18 | |
2001 | R2 | 0.481 | 0.335 | 0.067 | 0.318 | 0.32 | 0.159 |
p | 0.001 | 0.009 | 0.2821 | 0.018 | 0.018 | 0.1134 | |
n | 19 | 19 | 19 | 17 | 17 | 17 | |
2002 | R2 | 0.178 | 0.112 | 0.09 | 0.267 | 0.28 | 0.145 |
p | 0.056 | 0.137 | 0.184 | 0.019 | 0.017 | 0.097 | |
n | 21 | 21 | 21 | 20 | 20 | 20 | |
2003 | R2 | 0.104 | 0.012 | 0.01 | 0.157 | 0.02 | 0.001 |
p | 0.16 | 0.641 | 0.66 | 0.092 | 0.538 | 0.9924 | |
n | 20 | 20 | 20 | 19 | 19 | 19 |
*Linear regression of fluoroquinolone (FQ) use versus percent resistance for hospitals. R2, coefficient of determination; n, number of hospitals. Bold indicates significant relationships (p<0.05). FQ-R P. aeruginosa, fluoroquinolone-resistant Pseudomonas aeruginosa; MRSA, methicillin-resistant Staphylococcus aureus.