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Volume 11, Number 9—September 2005

Molecular Epidemiology of SARS-associated Coronavirus, Beijing

Wei Liu*, Fang Tang*, Arnaud Fontanet†, Lin Zhan*, Tian-Bao Wang‡, Pan-He Zhang*, Yi-He Luan‡, Chao-Yang Cao‡, Qiu-Min Zhao*, Xiao-Ming Wu*, Zhong-Tao Xin§, Shu-Qing Zuo*, Laurence Baril†, Astrid Vabret¶, Yi-Ming Shao#, Hong Yang*, and Wu-Chun Cao*Comments to Author 
Author affiliations: *Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China; †Institut Pasteur, Paris, France; ‡Beijing Armed Force Hospital, Beijing, People's Republic of China; §Beijing Institute of Basic Medical Sciences, Beijing, People's Republic of China; ¶Caen University, Caen, France; #Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China

Main Article

Table 3

Characterization of nucleotide (nt) substitutions in 29 severe acute respiratory syndrome patients, Beijing, China*

ORF or protein Position† nt substitution aa change No. patients
ORF 1b 17620 C→T Leu→Ser 5
S protein 22077 G→T Phe→Tyr 9
S protein 22589 C→T Noncoding region 24
ORF 9 27749 G→A Lys→Glu 12

*SARS, severe acute respiratory syndrome; ORF, open reading frame; aa, amino acid.
†The nt positions are numbered with TOR2 as reference strain (accession no. NC_004718).

Main Article

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