Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 11, Number 9—September 2005
Research

Persistence of Resistant Staphylococcus epidermidis after Single Course of Clarithromycin

Maria Sjölund*†, Eva Tano*, Martin J. Blaser‡, Dan I. Andersson†, and Lars Engstrand*†Comments to Author 
Author affiliations: *University Hospital, Uppsala, Sweden; †The Swedish Institute for Infectious Disease Control, Solna, Sweden; ‡New York University School of Medicine, New York, New York, USA

Main Article

Table 2

Characteristics of Staphylococcus epidermidis isolated from controls*†

Control Pretreatment‡
 Posttreatment‡
 1 year posttreatment‡
 4 years posttreatment‡
Isolate MIC DNA Isolate MIC DNA Isolate MIC DNA Isolate MIC DNA
1 1A:1 0.064 – 1B:1 0.064 – 1C:1 0.094 FF 1D:1 0.064 JJ
1A:2 0.064 AA 1B:2 0.064 BB 1C:2 0.094 GG 1D:2 0.047 JJ
1A:3 0.064 – 1B:3 0.094 – 1C:3 0.047 GG 1D:3 0.064 JJ
1A:4 0.064 BB 1B:4 0.064 FF 1C:4 0.064 HH 1D:4 0.064 JJ
1A:5 0.064 CC 1B:5 0.047 BB 1C:5 0.064 HH 1D:5 0.094 JJ
1A:6 0.064 DD 1B:6 0.047 FF 1C:6 0.032 HH 1D:6 0.064 JJ
1A:7 0.047 – 1B:7 0.064 – 1C:7 0.032 HH 1D:7 0.064 JJ
1A:8 0.064 – 1B:8 0.064 FF 1C:8 0.047 HH 1D:8 0.064 JJ
1A:9 0.047 EE 1B:9 0.064 FF 1C:9 0.047 HH 1D:9 0.064 JJ
1A:10 0.064 CC 1B:10 0.047 – 1C:10 0.047 HH 1D:10 0.064 JJ
2 2A:1 0.094 KK 2B:1 0.094 KK 2C:1 0.094 LL 2D:1 0.094 KK
2A:2 0.047 LL 2B:2 0.064 LL 2C:2 0.047 OO 2D:2 0.094 KK
2A:3 0.094 LL 2B:3 0.064 – 2C:3 0.047 OO 2D:3 0.094 LL
2A:4 0.047 KK 2B:4 0.064 LL 2C:4 0.047 OO 2D:4 0.094 MM
2A:5 0.064 KK 2B:5 0.064 LL 2C:5 0.064 LL 2D:5 0.094 LL
2A:6 0.064 MM 2B:6 0.064 LL 2C:6 0.064 PP 2D:6 0.094 KK
2A:7 0.064 KK 2B:7 0.064 LL 2C:7 0.047 PP 2D:7 0.094 LL
2A:8 0.094 LL 2B:8 0.047 KK 2C:8 0.047 PP 2D:8 0.125 KK
2A:9 0.064 KK 2B:9 0.064 NN 2C:9 0.125 LL 2D:9 0.064 KK
2A:10 0.094 KK 2B:10 0.032 NN 2C:10 0.047 OO 2D:10 0.094 KK
3 3A:1 0.125 3B:1 0.125 3C:1 0.125 3D:1 0.125
3A:2 0.125 3B:2 0.125 3C:2 0.125 3D:2 0.125
3A:3 0.125 3B:3 0.125 3C:3 0.125 3D:3 0.125
3A:4 0.125 3B:4 0.125 3C:4 0.125 3D:4 0.125
3A:5 0.125 3B:5 0.125 3C:5 0.125 3D:5 0.25
3A:6 0.125 3B:6 0.125 3C:6 0.25 3D:6 0.25
3A:7 0.125 3B:7 0.25 3C:7 0.25 3D:7 0.25
3A:8 0.25 3B:8 0.25 3C:8 0.25 3D:8 0.25
3A:9 0.25 3B:9 0.25 3C:9 0.25 3D:9 0.25
3A:10 0.25 3B:10 0.25 3C:10 0.25 3D:10 0.25
4 4A:1 0.125 4B:1 0.125 4C:1 0.125 4D:1 0.125
4A:2 0.125 4B:2 0.125 4C:2 0.125 4D:2 0.125
4A:3 0.125 4B:3 0.125 4C:3 0.125 4D:3 0.125
4A:4 0.125 4B:4 0.125 4C:4 0.125 4D:4 0.125
4A:5 0.25 4B:5 0.125 4C:5 0.125 4D:5 0.125
4A:6 0.25 4B:6 0.25 4C:6 0.125 4D:6 0.125
4A:7 0.25 4B:7 0.25 4C:7 0.125 4D:7 0.125
4A:8 0.25 4B:8 0.25 4C:8 0.25 4D:8 0.125
4A:9 0.25 4B:9 >256 4C:9 0.25 4D:9 0.125
4A:10 >256 4B:10 >256 4C:10 0.25 4D:10 0.125
5 5A:1 0.125 5B:1 0.125 5C:1 0.125 5D:1 0.125
5A:2 0.125 5B:2 0.125 5C:2 0.125 5D:2 0.125
5A:3 0.125 5B:3 0.125 5C:3 0.125 5D:3 0.125
5A:4 0.125 5B:4 0.125 5C:4 0.125 5D:4 0.125
5A:5 0.125 5B:5 0.125 5C:5 0.125 5D:5 128
5A:6 0.125 5B:6 0.125 5C:6 0.125 5D:6 128
5A:7 0.125 5B:7 0.125 5C:7 0.125 5D:7 128
5A:8 0.125 5B:8 0.125 5C:8 0.125 5D:8 128
5A:9 0.125 5B:9 0.125 5C:9 0.125 5D:9 0.064
5A:10 0.25 5B:10 0.125 5C:10 0.125 5D:10 64

*Isolates from only 2 controls were DNA fingerprinted.
†Time points are defined with respect to treatment, although the control group received no treatment. For each control and time point, 10 independent isolations of S. epidermidis were performed.
‡Clarithromycin MIC measured by Etest. DNA fingerprinting by pulsed-field gel electrophoresis; different patterns are indicated as letters. –, not determined.

Main Article

Page created: April 23, 2012
Page updated: April 23, 2012
Page reviewed: April 23, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external