Volume 12, Number 11—November 2006
Research
Targeted Social Distancing Designs for Pandemic Influenza
Table 5
No. | Strategy combination | Base case ID factor | Variation 2 ID factor | Variation 1 ID factor | Variations 1 and 2 ID factor | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S | CTsd | AOAsd | LL | Wsd | 1 | 1.25 | 1.5 | 2 | 1 | 1.25 | 1.5 | 2 | 1 | 1.25 | 1.5 | 2 | 1 | 1.25 | 1.5 | 2 | |
1 | 51 | 66 | 75 | 86 | 52 | 68 | 78 | 88 | 52 | 70 | 80 | 90 | 52 | 70 | 80 | 90 | |||||
2 | Wsd | 48 | 63 | 72 | 84 | 41 | 60 | 71 | 83 | 47 | 66 | 77 | 88 | 35 | 58 | 72 | 86 | ||||
3 | LL | 41 | 57 | 67 | 79 | 37 | 57 | 68 | 82 | 36 | 57 | 70 | 84 | 28 | 55 | 69 | 84 | ||||
4 | LL | Wsd | 39 | 55 | 65 | 78 | 30 | 49 | 62 | 77 | 30 | 53 | 67 | 82 | 12 | 42 | 60 | 78 | |||
5 | AOAsd | 38 | 51 | 59 | 70 | 40 | 58 | 68 | 79 | 25 | 46 | 58 | 72 | 33 | 56 | 69 | 80 | ||||
6 | AOAsd | Wsd | 35 | 48 | 56 | 66 | 30 | 47 | 58 | 71 | 18 | 39 | 51 | 66 | 9 | 37 | 53 | 71 | |||
7 | AOAsd | LL | 32 | 46 | 55 | 66 | 28 | 48 | 60 | 73 | 13 | 36 | 50 | 67 | 11 | 40 | 57 | 74 | |||
8 | AOAsd | LL | Wsd | 30 | 43 | 52 | 63 | 21 | 40 | 51 | 66 | 10 | 32 | 46 | 62 | 4 | 23 | 42 | 64 | ||
9 | CTsd | 41 | 58 | 69 | 82 | 45 | 64 | 75 | 86 | 41 | 63 | 76 | 88 | 46 | 67 | 78 | 88 | ||||
10 | CTsd | Wsd | 37 | 55 | 66 | 79 | 31 | 53 | 66 | 80 | 32 | 57 | 71 | 85 | 21 | 52 | 67 | 83 | |||
11 | CTsd | LL | 29 | 48 | 60 | 75 | 26 | 50 | 64 | 78 | 20 | 47 | 63 | 80 | 19 | 49 | 65 | 81 | |||
12 | CTsd | LL | Wsd | 27 | 45 | 57 | 72 | 16 | 40 | 55 | 72 | 14 | 41 | 58 | 77 | 6 | 32 | 53 | 74 | ||
13 | CTsd | AOAsd | 29 | 46 | 56 | 68 | 34 | 55 | 66 | 78 | 15 | 40 | 54 | 70 | 27 | 54 | 67 | 79 | |||
14 | CTsd | AOAsd | Wsd | 26 | 42 | 52 | 64 | 20 | 41 | 54 | 69 | 9 | 31 | 45 | 63 | 5 | 30 | 50 | 69 | ||
15 | CTsd | AOAsd | LL | 22 | 39 | 51 | 64 | 18 | 42 | 56 | 72 | 7 | 29 | 45 | 64 | 7 | 35 | 55 | 73 | ||
16 | CTsd | AOAsd | LL | Wsd | 20 | 37 | 48 | 61 | 10 | 32 | 47 | 63 | 5 | 22 | 39 | 58 | 3 | 16 | 37 | 61 | |
17 | S | 41 | 61 | 73 | 85 | 45 | 66 | 77 | 87 | 47 | 68 | 79 | 90 | 51 | 69 | 80 | 90 | ||||
18 | S | Wsd | 36 | 57 | 70 | 83 | 30 | 54 | 68 | 83 | 38 | 62 | 75 | 88 | 29 | 56 | 71 | 85 | |||
19 | S | LL | 23 | 47 | 62 | 78 | 23 | 49 | 65 | 80 | 20 | 50 | 66 | 83 | 22 | 51 | 67 | 83 | |||
20 | S | LL | Wsd | 19 | 44 | 59 | 76 | 9 | 38 | 55 | 74 | 13 | 44 | 62 | 80 | 6 | 35 | 55 | 76 | ||
21 | S | AOAsd | 26 | 47 | 59 | 74 | 34 | 56 | 69 | 81 | 16 | 44 | 60 | 76 | 34 | 58 | 70 | 82 | |||
22 | S | AOAsd | Wsd | 20 | 41 | 55 | 70 | 14 | 41 | 57 | 73 | 8 | 35 | 52 | 71 | 7 | 36 | 55 | 74 | ||
23 | S | AOAsd | LL | 11 | 35 | 51 | 68 | 12 | 40 | 57 | 74 | 5 | 28 | 48 | 69 | 8 | 38 | 57 | 75 | ||
24 | S | AOAsd | LL | Wsd | 9 | 32 | 47 | 65 | 5 | 27 | 45 | 66 | 4 | 20 | 41 | 64 | 3 | 14 | 39 | 65 | |
25 | S | CTsd | 4 | 26 | 50 | 73 | 15 | 47 | 64 | 80 | 12 | 46 | 64 | 82 | 34 | 58 | 71 | 84 | |||
26 | S | CTsd | Wsd | 3 | 15 | 40 | 68 | 3 | 21 | 46 | 71 | 5 | 32 | 55 | 78 | 6 | 36 | 56 | 77 | ||
27 | S | CTsd | LL | 2 | 7 | 29 | 60 | 3 | 21 | 45 | 70 | 3 | 17 | 43 | 70 | 5 | 33 | 54 | 75 | ||
28 | S | CTsd | LL | Wsd | 2 | 6 | 20 | 54 | 2 | 6 | 24 | 57 | 2 | 9 | 31 | 64 | 2 | 9 | 33 | 64 | |
29 | S | CTsd | AOAsd | 2 | 4 | 13 | 44 | 4 | 24 | 48 | 70 | 2 | 4 | 15 | 49 | 8 | 37 | 56 | 73 | ||
30 | S | CTsd | AOAsd | Wsd | 2 | 3 | 7 | 30 | 2 | 5 | 16 | 49 | 2 | 3 | 6 | 28 | 2 | 5 | 20 | 54 | |
31 | S | CTsd | AOAsd | LL | 2 | 3 | 9 | 34 | 2 | 7 | 27 | 58 | 2 | 3 | 7 | 36 | 3 | 11 | 35 | 63 | |
32 | S | CTsd | AOAsd | LL | Wsd | 2 | 3 | 6 | 25 | 2 | 3 | 8 | 37 | 2 | 2 | 5 | 20 | 2 | 3 | 9 | 39
*Variation 2 is an increase in work group frequency of contact to give all children, teenagers, and adults the same overall contact frequencies; variation 1 is removal of relative infectivity and susceptibility. ID, disease infectivity; S, school closure; CTsd, children and teenagers social distancing; AOAsd, adults and older adults social distancing; LL, liberal leave; Wsd, work social distancing. Shaded numbers denote strategy combinations that reduce the attack rate to <10% of the population (illness attack rate <5%). Average attack rates accumulate over only those simulations that resulted in epidemics (>100 infected). Average standard deviation across the entire set of simulations was 2.2% with a maximum of 7.6%. |
*Variation 2 is an increase in work group frequency of contact to give all children, teenagers, and adults the same overall contact frequencies; variation 1 is removal of relative infectivity and susceptibility. ID, disease infectivity; S, school closure; CTsd, children and teenagers social distancing; AOAsd, adults and older adults social distancing; LL, liberal leave; Wsd, work social distancing. Shaded numbers denote strategy combinations that reduce the attack rate to <10% of the population (illness attack rate <5%). Average attack rates accumulate over only those simulations that resulted in epidemics (>100 infected). Average standard deviation across the entire set of simulations was 2.2% with a maximum of 7.6%.