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Volume 12, Number 3—March 2006

Research

Identifying and Quantifying Genotypes in Polyclonal Infections due to Single Species

James M. Colborn*, Ousmane Koita†, Ousmane Cissé†, Mamadou W. Bagayoko†, Edward J. Guthrie‡, and Donald J. Krogstad*Comments to Author 
Author affiliations: *Tulane University Health Sciences Center, New Orleans, Louisiana, USA; †University of Bamako, Bamako, Mali; ‡Agilent Technologies, Wilmington, Delaware, USA

Main Article

Figure 2

Copy numbers for genotypes of the K1 allotype in 10 field samples. Distribution of K1 genotypes within the 8 patients whose samples yielded amplicons with K1-specific primers (Table 4). These results indicate that most infected persons had >2 allotypes. In addition, persons with K1 allotype parasites had a high degree of genotypic complexity, that is, capillary electrophoresis showed up to 4 distinct K1 genotypes in the blood of individual patients at the same time.

Figure 2. Copy numbers for genotypes of the K1 allotype in 10 field samples. Distribution of K1 genotypes within the 8 patients whose samples yielded amplicons with K1-specific primers (Table 4). These results indicate that most infected persons had >2 allotypes. In addition, persons with K1 allotype parasites had a high degree of genotypic complexity, that is, capillary electrophoresis showed up to 4 distinct K1 genotypes in the blood of individual patients at the same time.

Main Article

Page created: January 27, 2012
Page updated: January 27, 2012
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