Volume 12, Number 5—May 2006
Letter
Extended-spectrum β-Lactamase–producing Enterobacteriaceae, Central African Republic
Table
Characteristics of extended-spectrum β-lactamase–producing Enterobacteriaceae in Bangui, Central African Republic
Strain† | Patient hospitalized | Results of sequencing |
MICs of β-lactams (μg/mL)* |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
blaCTX-M | blaSHV | blaTEM | AMC | CTX | CAZ | CRO | FEP | CPO | ATM | Resistance | ||
K. pneumoniae 022 | N | SHV-2a | TEM-1 | 16 | 16 | 16 | 16 | 8 | 8 | 2 | KGT | |
K. pneumoniae 043 | Y | SHV-12 | TEM-1 | 16 | 16 | 256 | 32 | 8 | 8 | 256 | KGTNC | |
K. pneumoniae 106 | Y | CTX-M-15 | TEM-1 | 8 | 256 | 128 | 256 | 64 | 256 | 64 | None | |
K. pneumoniae 047 | Y | SHV-2a | TEM-1 | 64 | 16 | 16 | 16 | 8 | 16 | 32 | None | |
E. coli 272 | Y | CTX-M-15 | TEM-1 | 32 | 256 | 128 | 256 | 128 | 256 | 128 | KGTNC | |
E. coli 065 | Y | CTX-M-15 | TEM-1 | 20 | 256 | 128 | 256 | 64 | 256 | 128 | C | |
E. coli 047 | N | CTX-M-15 | TEM-1 | 16 | 256 | 32 | 256 | 32 | 128 | 64 | KGTC | |
E. coli 010 | N | CTX-M-15 | TEM-1 | 32 | 256 | 128 | 256 | 128 | 256 | 256 | KGT | |
E. coli 073 | N | CTX-M-15 | TEM-1 | 16 | 256 | 128 | 256 | 128 | 256 | 128 | KGTC | |
E. coli 059 | Y | CTX-M-15 | TEM-1 | 19 | 256 | 128 | 256 | 8 | 256 | 256 | C | |
E. coli 064 | N | CTX-M-15 | TEM-1 | 128 | 256 | 128 | 256 | 64 | 256 | 64 | C | |
E. coli 070 | N | CTX-M-15 | TEM-1 | 128 | 256 | 128 | 256 | 64 | 256 | 128 | C | |
E. coli 054 | N | CTX-M-15 | TEM-1 | 128 | 256 | 32 | 256 | 64 | 256 | 32 | KGTC | |
E. coli 026 | N | CTX-M-15 | TEM-1 | 32 | 256 | 64 | 256 | 128 | 256 | 256 | KGTC | |
E. cloacae 081 | Y | SHV-12 | TEM-1 | 32 | 16 | 256 | 16 | 0.125 | 1 | 256 | KGTN | |
E. cloacae 106 | Y | SHV-12 | TEM-1 | 128 | 16 | 256 | 16 | 32 | 8 | 256 | KGT | |
E. aerogenes 014 | Y | CTX-M-3 | SHV-12 | TEM-1 | 128 | 256 | 256 | 256 | 32 | 256 | 128 | KGTN |
*AMC, amoxicillin + clavulanic acid (2 μg/mL); CTX, cefotaxime; CAZ, ceftazidime; CRO, ceftriaxone; FEP, cefepime; CPO, cefpirome; ATM, aztreonam; K, kanamycin; G, gentamicin; T, tobramycin; N, netilmicin; C, ciprofloxacin.
†On Klebsiella pneumoniae strains, polymerase chain reaction and sequencing for blaSHV genes were studied on Escherichia coli transconjugant or electroporant.