Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 12, Number 5—May 2006
Letter

Extended-spectrum β-Lactamase–producing Enterobacteriaceae, Central African Republic

Thierry Frank*, Guillaume Arlet†‡Comments to Author , Valerie Gautier†, Antoine Talarmin*, and Raymond Bercion*
Author affiliations: *Institut Pasteur de Bangui, Bangui, Central African Republic; †Université Pierre et Marie Curie (Paris VI), Paris, France; ‡Hôpital Tenon AP-HP, Paris, France

Main Article

Table

Characteristics of extended-spectrum β-lactamase–producing Enterobacteriaceae in Bangui, Central African Republic

Strain† Patient hospitalized Results of sequencing
 MICs of β-lactams (μg/mL)*
blaCTX-M blaSHV blaTEM AMC CTX CAZ CRO FEP CPO ATM Resistance
K. pneumoniae 022 N SHV-2a TEM-1 16 16 16 16 8 8 2 KGT
K. pneumoniae 043 Y SHV-12 TEM-1 16 16 256 32 8 8 256 KGTNC
K. pneumoniae 106 Y CTX-M-15 TEM-1 8 256 128 256 64 256 64 None
K. pneumoniae 047 Y SHV-2a TEM-1 64 16 16 16 8 16 32 None
E. coli 272 Y CTX-M-15 TEM-1 32 256 128 256 128 256 128 KGTNC
E. coli 065 Y CTX-M-15 TEM-1 20 256 128 256 64 256 128 C
E. coli 047 N CTX-M-15 TEM-1 16 256 32 256 32 128 64 KGTC
E. coli 010 N CTX-M-15 TEM-1 32 256 128 256 128 256 256 KGT
E. coli 073 N CTX-M-15 TEM-1 16 256 128 256 128 256 128 KGTC
E. coli 059 Y CTX-M-15 TEM-1 19 256 128 256 8 256 256 C
E. coli 064 N CTX-M-15 TEM-1 128 256 128 256 64 256 64 C
E. coli 070 N CTX-M-15 TEM-1 128 256 128 256 64 256 128 C
E. coli 054 N CTX-M-15 TEM-1 128 256 32 256 64 256 32 KGTC
E. coli 026 N CTX-M-15 TEM-1 32 256 64 256 128 256 256 KGTC
E. cloacae 081 Y SHV-12 TEM-1 32 16 256 16 0.125 1 256 KGTN
E. cloacae 106 Y SHV-12 TEM-1 128 16 256 16 32 8 256 KGT
E. aerogenes 014 Y CTX-M-3 SHV-12 TEM-1 128 256 256 256 32 256 128 KGTN

*AMC, amoxicillin + clavulanic acid (2 μg/mL); CTX, cefotaxime; CAZ, ceftazidime; CRO, ceftriaxone; FEP, cefepime; CPO, cefpirome; ATM, aztreonam; K, kanamycin; G, gentamicin; T, tobramycin; N, netilmicin; C, ciprofloxacin.
†On Klebsiella pneumoniae strains, polymerase chain reaction and sequencing for blaSHV genes were studied on Escherichia coli transconjugant or electroporant.

Main Article

Page created: January 12, 2012
Page updated: January 12, 2012
Page reviewed: January 12, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external