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Volume 12, Number 7—July 2006
Letter

Panton-Valentine Leukocidin Genes in Staphylococcus aureus

Damian C. Melles*Comments to Author , Willem B. van Leeuwen*, Hélène A.M. Boelens*, Justine K. Peeters*, Henri A. Verbrugh*, and Alex van Belkum*
Author affiliations: *University Medical Center Rotterdam, Rotterdam, the Netherlands

Main Article

Table

Panton-Valentine Leukocidin (PVL) distribution among carriage and invasive isolates per genetic cluster of Staphylococcus aureus

Amplified fragment length polymorphism cluster
I
(n = 462)
II
(n= 261)
III
(n = 208)
IVa
(n = 62)
IVb
(n = 40)
Total
(N = 1,033)
PVL positive, n (%)
Carriage isolates
(n = 829) 1 1 1 0 2 5 (0.6)*
Bacteremia isolates
(n = 146) 1 1 0 0 1 3 (2.1)†
Soft tissue infection isolates
(n = 18) 1 5 0 1 0 7 (38.9)‡
Impetigo isolates
(n = 40) 0 0 0 0 0 0 (0.0)
Total
(N = 1,033) 3 (0.6)§ 7 (2.7) 1 (0.5)¶ 1 (1.6) 3 (7.5)# 15 (1.5)
MLST** data of PVL-positive isolates CC 1, n = 2
CC 8, n = 1 CC 30, n = 7 CC 45, n = 1 CC 22, n = 1 CC 121, n = 3

‡versus *Fisher exact test (2-sided); p<0.0001.
‡versus †Fisher exact test (2-sided); p<0.0001.
#versus §Fisher exact test (2-sided); p = 0.0079.
#versus ¶Fisher exact test (2-sided); p = 0.0140.
**MLST, multilocus sequence typing; CC, clonal complex.

Main Article

Page created: December 16, 2011
Page updated: December 16, 2011
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