Volume 12, Number 7—July 2006
Dispatch
Smallpox during Pregnancy and Maternal Outcomes
Table 1
Case fatality among pregnant women with smallpox by gestational age, according to data from 19th- and early 20th-century outbreaks*
Reference | Gestational age <3 mo |
Gestational age 4–6 mo |
Gestational age 7–9 mo |
|||
---|---|---|---|---|---|---|
D/C | CF (95% CI) | D/C | CF (95% CI) | D/C | CF (95% CI) | |
Meyer (9), 1868–1872 | 3/33 | 9.0 (0.0–18.9) | 11/33 | 33.3 (17.2–49.4) | 8/10 | 80.0 (55.2–100.0) |
Welch (10), 1878 | 4/12 | 33.3 (6.7–60.0) | 4/22 | 18.2 (2.1–34.3) | 6/12 | 50.0 (21.7–78.3) |
Queirel (18), 1906 | 2/4 | 50.0 (1.0–99.0) | 7/10 | 14.5 (41.6–98.4) | 1/5 | 17.9 (0.0–55.1) |
Rao (5), 1959–1962 | 7/21 | 33.3 (13.2–53.5) | 16/65 | 24.6 (14.1–35.1) | 34/94 | 36.2 (26.5–45.9) |
Total | 16/70 | 22.9 (2.3–43.4) | 38/130 | 29.2 (14.8–43.7) | 49/121 | 40.5 (26.8–54.2) |
*D/C, smallpox deaths/cases; CF, case fatality; CI, confidence interval.
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