Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 12, Number 8—August 2006
Research

Antibody Response to Pneumocystis jirovecii

Kieran R. Daly*†, Laurence Huang‡, Alison Morris§, Judy Koch*†, Kristina Crothers‡¶, Linda Levin†, Shary Eiser‡, Supriya Satwah†, Patrizia Zucchi‡#, and Peter D. Walzer*†Comments to Author 
Author affiliations: *Veterans Affairs Medical Center, Cincinnati, Ohio, USA; †University of Cincinnati, Cincinnati, Ohio, USA; ‡University of California, San Francisco, California, USA; §University of Southern California, Los Angeles, California, USA; ¶Yale University School of Medicine, New Haven, Connecticut, USA; #University of Pavia, Pavia, Italy

Main Article

Table 1

Demographic characteristics and baseline clinical measurements of patients with Pneumocystis pneumonia (PCP) and controls*

Characteristic PCP (n = 80) Controls
(n = 41)
Demographic
Male (%) 86 76
Race (%)
Caucasian 55 39
African American 29 39
Other 16 22
Age at enrollment (y) 41 ± 8 42 ± 8
Clinical
CD4 count (cells/μL)†‡ 29 ± 3 73 ± 4
Plasma HIV RNA (copies/mL)†‡ 123,130 ± 5 15,582 ± 24
Albumin (g/L) 3.0 ± 0.5 3.1 ± 0.7
Prior PCP (%) 24 33
Pneumonia severity
pO2 (mm Hg) 65 ± 15.6 73 ± 29
Aa gradient (mm Hg) 44 ± 13 41 ± 15
LDH (U/L)†‡ 359 ± 2 257 ± 2
Mechanical ventilation (%) 7 7
Serum antibody levels
MsgA† 5.6 ± 4.8 3.7 ± 3.5
MsgB† 2.9 ± 1.3 1.9 ± 0.9
MsgC† 4.2 ± 4.3 4.3 ± 3.4

*Unless specified otherwise, values are mean ± standard deviation. pO2, oxygen pressure; Aa, alveolar-arterial; LDH, lactate dehydrogenase; Msg, major surface glycoprotein.
†Geometric mean ± geometric standard deviation.
‡Significant difference between patient groups for CD4+ count (p<0.01), plasma HIV RNA (p<0.001), LDH (p<0.001).

Main Article

Page created: December 09, 2011
Page updated: December 09, 2011
Page reviewed: December 09, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external