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Volume 13, Number 1—January 2007
Dispatch
Ophthalmic Surgery in Prion Diseases
Tsuyoshi Hamaguchi*1, Moeko Noguchi-Shinohara*, Yosikazu Nakamura†2, Takeshi Sato‡2, Tetsuyuki Kitamoto§2, Hidehiro Mizusawa¶2, and Masahito Yamada*2
Table 2
Clinical symptoms of sCJD within 2 mo after disease onset*
| Characteristic | Ophthalmic surgery |
Total | p value | |
|---|---|---|---|---|
| No, n = 458 | Yes, n = 10 | |||
| Female/male | 263/195 | 6/4 | 269/199 | 0.57 |
| Age at onset, y; mean ± SD | 66.8 ± 9.9 | 68.3 ± 9.1 | 66.8 ± 9.9 | 0.74 |
| Disease duration,† mean ± SD | 4.2 ± 4.8 | 9.1 ± 6.0 | 4.3 ± 4.9 | 0.0004 |
| Clinical symptoms (%) | ||||
| Dementia (+)/visual impairment (+) | 153 (34.2) | 4 (40.0) | 157 (34.3) | |
| Dementia (+)/visual impairment (–) | 239 (53.3) | 3 (30.0) | 242 (52.8) | 0.0004 |
| Dementia (–)/visual impairment (+) | 16 (3.6) | 3 (30.0) | 19 (4.1) | |
| Dementia (–)/visual impairment (–) | 40 (8.9) | 0 | 40 (8.7) | |
*sCJD, sporadic Creutzfeldt-Jakob disease; SD, standard deviation; +, with; –, without.
†Disease duration, the duration from onset to akinetic mutism or death if patients never displayed akinetic mutism.
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