Volume 13, Number 1—January 2007
Dispatch
Ophthalmic Surgery in Prion Diseases
Table 2
Clinical symptoms of sCJD within 2 mo after disease onset*
Characteristic | Ophthalmic surgery |
Total | p value | |
---|---|---|---|---|
No, n = 458 | Yes, n = 10 | |||
Female/male | 263/195 | 6/4 | 269/199 | 0.57 |
Age at onset, y; mean ± SD | 66.8 ± 9.9 | 68.3 ± 9.1 | 66.8 ± 9.9 | 0.74 |
Disease duration,† mean ± SD | 4.2 ± 4.8 | 9.1 ± 6.0 | 4.3 ± 4.9 | 0.0004 |
Clinical symptoms (%) | ||||
Dementia (+)/visual impairment (+) | 153 (34.2) | 4 (40.0) | 157 (34.3) | |
Dementia (+)/visual impairment (–) | 239 (53.3) | 3 (30.0) | 242 (52.8) | 0.0004 |
Dementia (–)/visual impairment (+) | 16 (3.6) | 3 (30.0) | 19 (4.1) | |
Dementia (–)/visual impairment (–) | 40 (8.9) | 0 | 40 (8.7) |
*sCJD, sporadic Creutzfeldt-Jakob disease; SD, standard deviation; +, with; –, without.
†Disease duration, the duration from onset to akinetic mutism or death if patients never displayed akinetic mutism.
1Current affiliation: Ishikawa Prefecture Central Hospital, Kanazawa, Japan
2Member, Creutzfeldt-Jakob Disease Surveillance Committee, Japan