Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 13, Number 4—April 2007
Research

Influenza (H5N1) Viruses in Poultry, Russian Federation, 2005–2006

Aleksandr S. Lipatov*12, Vasily A. Evseenko†1, Hong Wang*, Anna V. Zaykovskaya†, Alexander G. Durimanov†, Sergey I. Zolotykh†, Sergey V. Netesov†, Ilya G. Drozdov†, Gennadiy G. Onishchenko‡, Robert G. Webster*Comments to Author , and Alexander M. Shestopalov†

Author affiliations: *St Jude Children’s Research Hospital, Memphis, Tennessee, USA; †Federal State Research Institute Research Center for Virology and Biotechnology “Vector,” Koltsovo, Novosibirsk Region, Russian Federation; ‡Federal Service for Surveillance in Consumer Rights Protection and Human Well-being, Moscow, Russian Federation;

Main Article

Table 2

Pathogenicity and replication of influenza (H5N1) viruses in mice*

Virus Log10 EID50/mL MID50† MLD50† Titers in mouse organs‡
Lungs Spleen Brain Liver Kidney
A/goose/Krasnoozerskoye/627/2005
 9.2
 102.2
 102.3
 6.1±0.3
 1.6±0.5
 5.2±0.2
 1.6±0.3
 2.6±0.2
A/turkey/Suzdalka/12/2005
 9.3
 105.3
 106.3
 4.1±0.6
 <1
 2.3±0.5
 <1
 <1
A/chicken/Krasnodar/123/2006 8.4 102.1 102.3 4.7±0.3 <1 <1 <1 <1

*EID50, 50% egg infectious dose; MID50, 50% mouse infectious dose; MLD50, 50% mouse lethal dose.
†The 50% mouse infective dose (MID50) and mouse lethal dose (MLD50) are expressed as number of EID50. Values are the means of 2 titration experiments.
‡Mean ± SD from 3 mice, expressed as log10 EID50/0.1 mg of organ tissue.

Main Article

1These authors contributed equally to this work.

2Current affiliation: US Department of Agriculture, Athens, Georgia, USA

Page created: June 28, 2010
Page updated: June 28, 2010
Page reviewed: June 28, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external