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Volume 13, Number 5—May 2007
Research

Pet Rodents and Fatal Lymphocytic Choriomeningitis in Transplant Patients

Brian R. Amman*1Comments to Author , Boris I. Pavlin*12, Cesar G. Albariño*, James A. Comer*, Bobbie R. Erickson*, Jennifer B. Oliver*, Tara K. Sealy*, Martin J. Vincent*, Stuart T. Nichol*, Christopher D. Paddock*, Abbigail J. Tumpey*, Kent D. Wagoner*3, R. David Glauer†, Kathleen A. Smith‡, Kim A. Winpisinger‡, Melody S. Parsely§, Phil Wyrick¶, Christopher H. Hannafin#, Utpala Bandy**, Sherif Zaki*, Pierre E. Rollin*, and Thomas G. Ksiazek*

Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Ohio Department of Agriculture, Reynoldsburg, Ohio, USA; ‡Ohio Department of Health, Columbus, Ohio, USA; §Arkansas Department of Health and Human Services, Little Rock, Arkansas, USA; ¶Arkansas Department of Agriculture, Little Rock, Arkansas, USA; #Rhode Island Department of Environmental Management, Providence, Rhode Island, USA; **Rhode Island Department of Public Health, Providence, Rhode Island, USA;

Main Article

Table 2

Results of laboratory testing on the index hamster and traceback rodents associated with organ transplantation transmission of LCMV*

Rodent† IFA ELISA IHC RT-PCR/ TaqMan Virus
isolation Sequence
(L gene)
Index hamster
 ND
 Neg
 Pos
 Pos
 Pos
 232 bp
Pet store hamster 1
 Pos
 Neg
 Pos
 Pos
 Pos
 232 bp
Pet store hamster 2
 Neg
 Neg
 Pos
 Pos
 Pos
 232 bp
Pet store guinea pig 1
 ND
 Neg
 Pos
 Pos
 Pos
 232 bp
Ohio hamster 1
 Pos
 Neg
 Pos
 Pos
 Pos
 232 bp
Ohio Hamster 2
 Pos
 Neg
 Pos
 Pos
 Pos
 NA
Ohio hamster 3
 Pos
 Neg
 ND
 Neg
 Neg
 NA
Ohio hamster 4
 Neg
 Neg
 Pos
 Pos
 Pos
 NA
Ohio hamster 5 Neg Neg Neg ND Pos NA

*LCMV, lymphocytic choriomeningitis virus; IFA, immunofluorescent antibody assay; IHC, immunohistochemistry; RT-PCR, reverse transcription–PCR; ND, no data; Neg, negative; Pos, positive; NA, no amplification (could not get traditional PCR primers to amplify, for sequencing).
†The table includes only those rodents that tested positive with ≥1 test.

Main Article

1These authors contributed equally to this article.

2Current affiliation: Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

3Current affiliation: Ithaca College, Ithaca, New York, USA

Page created: June 23, 2010
Page updated: June 23, 2010
Page reviewed: June 23, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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