Volume 13, Number 6—June 2007
Research
Minority-Variant pfcrt K76T Mutations and Chloroquine Resistance, Malawi
Jonathan J. Juliano*, Jesse J. Kwiek*, Kathryn Cappell*, Victor Mwapasa†, and Steven R Meshnick*
Table 3
Detection of pfcrt 76T in clinical samples*
| Clinical site | No. samples | No. positive samples by HTA (%) | No. positive samples by ARPCR (%) | Avg mutant population by HTA (%) | SD |
|---|---|---|---|---|---|
| MHP | 27 | 1 (3.7)† | 0 (0) | 3.2 | 0.07 |
| MM | 60 | 21 (35)† | 0 (0) | 3.3 | 1.4 |
*HTA, heteroduplex tracking assay; ARPCR, standard allele-restricted PCR; MHP, Malaria and HIV in Pregnancy; MM, Mpemba and Madziabango.
†p = 0.001, Fisher exact test.
Page created: May 31, 2011
Page updated: May 31, 2011
Page reviewed: May 31, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.