Volume 14, Number 10—October 2008
Research
Cryptosporidium Species and Subtypes and Clinical Manifestations in Children, Peru
Table 5
Associations between infections with Cryptosporidium spp. or C. hominis subtype families and clinical manifestations expressed as incidence rate ratios in 533 children, Peru*
Clinical manifestation | First infection |
All infections |
|||
---|---|---|---|---|---|
IRR | p value | IRR | p value | ||
Children infected with C. hominis vs. those with cryptosporidiosis but not infected with C. hominis | |||||
Nausea | 5.469 | <0.001† | 3.531 | 0.037‡ | |
Vomiting | 2.252 | <0.001† | 2.359 | 0.023‡ | |
General malaise | 2.523 | <0.001† | 2.071 | 0.035‡ | |
Diarrhea |
3.690 |
<0.001† |
4.886 |
<0.001† |
|
Children infected with C. parvum vs. those with cryptosporidiosis but not infected with C. parvum | |||||
Diarrhea |
3.249 |
<0.001† |
4.562 |
<0.01† |
|
Children infected with C. meleagridis vs. those with cryptosporidiosis but not infected with C. meleagridis | |||||
Diarrhea |
2.484 |
0.006† |
7.684 |
<0.001† |
|
Children infected with C. canis or C. felis vs. those with cryptosporidiosis but not infected with these species | |||||
Diarrhea |
3.122 |
0.002† |
1.528 |
0.662 |
|
Children infected with C. hominis subtype family Ia vs. those not infected with that subtype family | |||||
Nausea | 5.020 | <0.001† | 3.203 | 0.183 | |
Vomiting | 2.280 | 0.013‡ | 2.100 | 0.141 | |
Diarrhea |
2.442 |
<0.001† |
3.061 |
0.002† |
|
Children infected with C. hominis subtype family Ib vs. those not infected with that subtype family | |||||
Nausea | 12.516 | <0.001† | 8.402 | 0.006† | |
Vomiting | 4.752 | <0.001† | 4.868 | 0.004† | |
General malaise | 4.939 | <0.001† | 4.139 | 0.006† | |
Diarrhea |
5.510 |
<0.001† |
6.506 |
<0.001† |
|
Children infected with C. hominis subtype family Id vs. those not infected with that subtype family | |||||
Diarrhea |
2.999 |
<0.001† |
3.171 |
0.022‡ |
|
Children infected with C. hominis subtype family Ie vs. those not infected with that subtype family | |||||
General malaise | 1.830 | 0.010‡ | 1.613 | 0.333 | |
Diarrhea | 3.117 | <0.001† | 4.160 | 0.001† |
*Determined by Poisson regression analyses. IRR, incidence rate ratio.
†Statistically significant at Bonferroni corrected α = 0.01.
‡Statistically significant at p<0.05.